D-GsMTx-4

Gly-D-Cys-D-Leu-D-Glu-D-Phe-D-Trp-D-Trp-D-Lys-D-Cys-D-Asn-D-Pro-D-Asn-D-Asp-D-Asp-D-Lys-D-Cys-D-Cys-D-Arg-D-Pro-D-Lys-D-Leu-D-Lys-D-Cys-D-Ser-D-Lys-D-Leu-D-Phe-D-Lys-D-Leu-D-Cys-D-Asn-D-Phe-D-Ser-D-Phe-NH2
: (M.W. 4095.8) C₁₈₅H₂₇₃N₄₉O₄₅S₆
: Inhibitor of Mechanosensitive Ion Channels (e.g. Piezo2)

Package	Price(Yen)	Availability	Quantity
Vial 0.1 mg	50,000	Ships within 1-3 business days
バルク見積もり

Solubility: H₂O (0.1 mM)

T.M. Suchyna, S.E. Tape, R.E.II Koeppe, O.S. Andersen, F. Sachs, and P.A. Gottlieb, Nature, 430, 235 (2004). (Original)
C.L. Bowman, P.A. Gottlieb, T.M. Suchyna, Y.K. Murphy, and F. Sachs, Toxicon, 49, 249 (2007). (Review)
C. Bae, F. Sachs, and P.A. Gottlieb, Biochemistry, 50, 6295 (2011). (Piezo1 Channel Inhibitor)
R. Gnanasambandam, C. Ghatak, A. Yasmann, K. Nishizawa, F. Sachs, A.S. Ladokhin, S.I. Sukharev, and T.M. Suchyna, Biophys. J., 112, 31 (2017). (Mechanism Study of Inhibiting Mechanosensitive Ion Channels)
C. Alcaino, K. Knutson, P.A. Gottlieb, G. Farrugia, and A. Beyder, Channels, 11, 245 (2017). (Piezo2 Channel Inhibitor)
M.M. Maneshi, L. Ziegler, F. Sachs, S.Z. Hua, and P.A. Gottlieb, Sci. Rep., 8, 14267 (2018).