4525-s D-GsMTx-4

Code:
4525-s
Name:
D-GsMTx-4
Gly-D-Cys-D-Leu-D-Glu-D-Phe-D-Trp-D-Trp-D-Lys-D-Cys-D-Asn-D-Pro-D-Asn-D-Asp-D-Asp-D-Lys-D-Cys-D-Cys-D-Arg-D-Pro-D-Lys-D-Leu-D-Lys-D-Cys-D-Ser-D-Lys-D-Leu-D-Phe-D-Lys-D-Leu-D-Cys-D-Asn-D-Phe-D-Ser-D-Phe-NH2
(M.W. 4095.8) C185H273N49O45S6
Inhibitor of Mechanosensitive Ion Channels (e.g. Piezo2)
Package Price(Yen)
Vial 0.1 mg 50,000

main

Purity:
≧95.0% (HPLC)
Storage:
-20 ℃

Solubility: H2O (0.1 mM)

more information

CAS Registry Number:
873785-93-4
Category:
Biologically Active Peptides

reference

  1. T.M. Suchyna, S.E. Tape, R.E.II Koeppe, O.S. Andersen, F. Sachs, and P.A. Gottlieb, Nature, 430, 235 (2004). (Original)
  2. C.L. Bowman, P.A. Gottlieb, T.M. Suchyna, Y.K. Murphy, and F. Sachs, Toxicon, 49, 249 (2007). (Review)
  3. C. Bae, F. Sachs, and P.A. Gottlieb, Biochemistry, 50, 6295 (2011). (Piezo1 Channel Inhibitor)
  4. R. Gnanasambandam, C. Ghatak, A. Yasmann, K. Nishizawa, F. Sachs, A.S. Ladokhin, S.I. Sukharev, and T.M. Suchyna, Biophys. J., 112, 31 (2017). (Mechanism Study of Inhibiting Mechanosensitive Ion Channels)
  5. C. Alcaino, K. Knutson, P.A. Gottlieb, G. Farrugia, and A. Beyder, Channels, 11, 245 (2017). (Piezo2 Channel Inhibitor)
  6. M.M. Maneshi, L. Ziegler, F. Sachs, S.Z. Hua, and P.A. Gottlieb, Sci. Rep., 8, 14267 (2018).