Epoxomicin

Code:
4381-v
Name:
Epoxomicin
(2R)-2-[Acetyl-(N-methyl-L-isoleucyl)-L-isoleucyl-L-threonyl-L-leucyl]-2-methyloxirane
(M.W. 554.72) C28H50N4O7
Inhibitor for Proteasome
Package Price(Yen) Availability Quantity  
Vial 0.2 mg 20,000 Ships within
1-3 business days
バルク見積もり

main

Purity:
≧95.0% (HPLC)
Other Name:
エポキソミシン
Storage:
-20 ℃
Production:
Synthetic Product

Solubility: DMSO (1 mM)

more information

Structure:
構造図Epoxomicin
Category:
Enzyme Inhibitors

reference

  1. L. Meng, R. Mohan, B.H.B. Kwok, M. Elofsson, N. Sin, and C.M. Crews, Proc. Natl. Acad. Sci. USA, 96, 10403 (1999). (Proteasome Inhibitor & Antiinflammatory Activity)
  2. N. Sin, K.B. Kim, M. Elofsson, L. Meng, H. Auth, B.H.B. Kwok, and C.M. Crews, Bioorg. Med. Chem. Lett., 9, 2283 (1999). (Proteasome Inhibitor)
  3. K.B. Kim, J. Myung, N. Sin, and C.M. Crews, Bioorg. Med. Chem. Lett., 9, 3335 (1999). (Proteasome Inhibitor)
  4. M. Groll, K.B. Kim, N. Kairies, R. Huber, and C.M. Crews, J. Am.Chem. Soc., 122, 1237 (2000). (Crystal Structure of Proteasome Complex)
  5. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).

関連書類

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