4381-v Epoxomicin

Code:
4381-v
Name:
Epoxomicin
(2R)-2-[Acetyl-(N-methyl-L-isoleucyl)-L-isoleucyl-L-threonyl-L-leucyl]-2-methyloxirane
(M.W. 554.72) C28H50N4O7
Inhibitor for Proteasome
Package Price(Yen)
Vial 0.2 mg 20,000

main

Purity:
≧95.0% (HPLC)
Other Name:
エポキソミシン
Storage:
-20 ℃
Production:
Synthetic Product

Solubility: DMSO (1 mM)

more information

Structure:
構造図Epoxomicin
CAS Registry Number:
134381-21-8
Category:
Enzyme Inhibitors

reference

  1. L. Meng, R. Mohan, B.H.B. Kwok, M. Elofsson, N. Sin, and C.M. Crews, Proc. Natl. Acad. Sci. USA, 96, 10403 (1999). (Proteasome Inhibitor & Antiinflammatory Activity)
  2. N. Sin, K.B. Kim, M. Elofsson, L. Meng, H. Auth, B.H.B. Kwok, and C.M. Crews, Bioorg. Med. Chem. Lett., 9, 2283 (1999). (Proteasome Inhibitor)
  3. K.B. Kim, J. Myung, N. Sin, and C.M. Crews, Bioorg. Med. Chem. Lett., 9, 3335 (1999). (Proteasome Inhibitor)
  4. M. Groll, K.B. Kim, N. Kairies, R. Huber, and C.M. Crews, J. Am.Chem. Soc., 122, 1237 (2000). (Crystal Structure of Proteasome Complex)
  5. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).