Lipid A (Alcaligenes faecalis)
- Code:
- 24018-s
- Name:
- Lipid A (Alcaligenes faecalis)
- 2-[(R)-3-(Decanoyloxy)tetradecanoylamino]-2-deoxy-6-O-(2-deoxy-2-{(R)-3-[(R)-3-hydroxydodecanoyloxy]tetradecanoylamino}-3-O-[(R)-3-hydroxytetradecanoyl]-β-D-glucopyranosyl)-3-O-[(R)-3-hydroxytetradecanoyl]-α-D-glucopyranose 1,4′-bisphosphate
- (Triethylammonium Form)
- (M.W. 1758.3) C90H170N2O26P2
- Vaccine Adjuvant Candidate / Active Principle of Low-Toxic Endotoxin
- main
- more information
- reference
main
- Storage:
- -20 ℃
- Source:
- Alcaligenes faecalis
Solubility: DMSO (0.1 mM)
more information
- Structure:
- Category:
- Carbohydrates and Conjugates
This compound is distributed under the license of National Institutes of Biomedical Innovation, Health and Nutrition and The Research Foundation for Microbial Diseases of Osaka University.
reference
- Y. Wang, K. Hosomi, A. Shimoyama, K. Yoshii, H. Yamaura, T. Nagatake, T. Nishino, H. Kiyono, K. Fukase, and J. Kunisawa, Vaccines, 8, 395 (2020). (Adjuvant Activity)
- K. Yoshii, K. Hosomi, A. Shimoyama, Y. Wang, H. Yamaura, T. Nagatake, H. Suzuki, H. Lan, H. Kiyono, K. Fukase, and J. Kunisawa, Microorganisms, 8, 1102 (2020). (Adjuvant Activity)
- A. Shimoyama, F. Di Lorenzo, H. Yamaura, K. Mizote, A. Palmigiano, M.D. Pither, I. Speciale, T. Uto, S. Masui, L. Sturiale, D. Garozzo, K. Hosomi, N. Shibata, K. Kabayama, Y. Fujimoto, A. Silipo, J. Kunisawa, H. Kiyono, A. Molinaro, and K. Fukase, Angew. Chem. Int. Ed., 60, 10023 (2021). (Chem. Synthesis)
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