Lipid A (Alcaligenes faecalis)

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Code:: 24018-s
Name:: Lipid A (Alcaligenes faecalis)

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2-[(R)-3-(Decanoyloxy)tetradecanoylamino]-2-deoxy-6-O-(2-deoxy-2-{(R)-3-[(R)-3-hydroxydodecanoyloxy]tetradecanoylamino}-3-O-[(R)-3-hydroxytetradecanoyl]-β-D-glucopyranosyl)-3-O-[(R)-3-hydroxytetradecanoyl]-α-D-glucopyranose 1,4′-bisphosphate
: (Triethylammonium Form)
: (M.W. 1758.3) C₉₀H₁₇₀N₂O₂₆P₂
: Vaccine Adjuvant Candidate / Active Principle of Low-Toxic Endotoxin

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Vial 0.1 mg	25,000	Ships within 1-3 business days
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Storage:: -20 ℃
Source:: Alcaligenes faecalis

Solubility: DMSO (0.1 mM)

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Structure:
Category:: Carbohydrates and Conjugates

This compound is distributed under the license of National Institutes of Biomedical Innovation, Health and Nutrition and The Research Foundation for Microbial Diseases of Osaka University.

reference

Y. Wang, K. Hosomi, A. Shimoyama, K. Yoshii, H. Yamaura, T. Nagatake, T. Nishino, H. Kiyono, K. Fukase, and J. Kunisawa, Vaccines, 8, 395 (2020). (Adjuvant Activity)
K. Yoshii, K. Hosomi, A. Shimoyama, Y. Wang, H. Yamaura, T. Nagatake, H. Suzuki, H. Lan, H. Kiyono, K. Fukase, and J. Kunisawa, Microorganisms, 8, 1102 (2020). (Adjuvant Activity)
A. Shimoyama, F. Di Lorenzo, H. Yamaura, K. Mizote, A. Palmigiano, M.D. Pither, I. Speciale, T. Uto, S. Masui, L. Sturiale, D. Garozzo, K. Hosomi, N. Shibata, K. Kabayama, Y. Fujimoto, A. Silipo, J. Kunisawa, H. Kiyono, A. Molinaro, and K. Fukase, Angew. Chem. Int. Ed., 60, 10023 (2021). (Chem. Synthesis)

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Data Sheet

SDS: Japanese / English

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