Novel Cancer Imaging Probe; 2-NBDLG 2016/02/02
2-NBDG (code 23002-v) has been widely utilized for monitoring D-glucose uptake in a variety of mammalian cells1). 2-NBDLG (code 23003-v), an antipode of 2-NBDG, was initially developed as the control substrate derived from L-glucose which is not used as major source of energy2, 3).
Surprisingly, 2-NBDLG uptake into spheroid-forming MIN6 insulinoma was found out by Yamada et al.4, 5). Moreover, Onoe et al. showed that a high contrast between a tumor cell (C6 glioma) and a normal one in tumor model mouse can be obtained by administration of 2-NBDLG4).
Imaging method using 2-NBDLG is expected as a new diagnostics of cancers.
|23002-v||2-NBDG||0.5 mg vial||5,000|
|23003-v||2-NBDLG||0.5 mg vial||15,000|