Exendin (9-39)
- Code:
- 4526-v
- Name:
- Exendin (9-39)
- Exendin-3 (9-39) amide, Avexitide
- Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
- (M.W. 3369.8) C149H234N40O47S
- GLP-1 Receptor Antagonist
- main
- more information
- reference
main
- Purity:
- ≧98.0% (HPLC)
- Storage:
- -20 ℃
- Source:
- Lizard, Heloderma horridum
Solubility: 1% AcOH or 10% DMSO (0.1 mM)
more information
- Category:
- Biologically Active Peptides
reference
- J.-P. Raufman, L. Singh, and J. Eng, J. Biol. Chem., 266, 2897 (1991). (Original)
- R. Göke, H.-C. Fehmann, T. Linn, H. Schmidt, M. Krause, J. Eng, and B. Göke, J. Biol. Chem., 268, 19650 (1993). (Validation as GLP-1 Receptor Antagonist)
- M.D. Turton, D. O'Shea, I. Gunn, S.A. Beak, C.M.B. Edwards, K. Meeran, S.J. Choi, G.M. Taylor, M.M. Heath, P.D. Lambert, J.P.H. Wilding, D.M. Smith, M.A. Ghatei, J. Herbert, and S.R. Bloom, Nature, 379, 69 (1996).
- L.S. Gasbjerg, E.J. Bari, M. Christensen, and F.K. Knop, Diabetes Obes. Metab., 23, 2419 (2021). (Review)
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