4526-v Exendin (9-39)

Code:
4526-v
Name:
Exendin (9-39)
Exendin-3 (9-39) amide, Avexitide
Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
(M.W. 3369.8) C149H234N40O47S
GLP-1 Receptor Antagonist
Package Price(Yen)
Vial 0.5 mg 30,000

main

Purity:
≧98.0% (HPLC)
Storage:
-20 ℃
Source:
Lizard, Heloderma horridum

Solubility: 1% AcOH or 10% DMSO (0.1 mM)

more information

CAS Registry Number:
133514-43-9
Category:
Biologically Active Peptides

reference

  1. J.-P. Raufman, L. Singh, and J. Eng, J. Biol. Chem., 266, 2897 (1991). (Original)
  2. R. Göke, H.-C. Fehmann, T. Linn, H. Schmidt, M. Krause, J. Eng, and B. Göke, J. Biol. Chem., 268, 19650 (1993). (Validation as GLP-1 Receptor Antagonist)
  3. M.D. Turton, D. O'Shea, I. Gunn, S.A. Beak, C.M.B. Edwards, K. Meeran, S.J. Choi, G.M. Taylor, M.M. Heath, P.D. Lambert, J.P.H. Wilding, D.M. Smith, M.A. Ghatei, J. Herbert, and S.R. Bloom, Nature, 379, 69 (1996).
  4. L.S. Gasbjerg, E.J. Bari, M. Christensen, and F.K. Knop, Diabetes Obes. Metab., 23, 2419 (2021). (Review)