α-Defensin-5 (Human)

Code:
4415-s
Name:
α-Defensin-5 (Human)
HD-5 (Human Defensin-5)
Ala-Thr-Cys-Tyr-Cys-Arg-Thr-Gly-Arg-Cys-Ala-Thr-Arg-Glu-Ser-Leu-Ser-Gly-Val-Cys-Glu-Ile-Ser-Gly-Arg-Leu-Tyr-Arg-Leu-Cys-Cys-Arg (Disulfide bonds between Cys3-Cys31, Cys5-Cys20, and Cys10-Cys30)
(M.W. 3582.1) C144H238N50O45S6
Antimicrobial Peptide in Paneth Cells
Package Price(Yen) Availability Quantity  
Vial 0.1 mg 22,000 Ships within
1-3 business days

main

Purity:
≧99.0% (HPLC)
View Analytical Data Sheet
Other Name:
α-ディフェンシン-5
α-デフェンシン-5
Storage:
-20 ℃
Production:
Synthetic Product

more information

CAS Registry Number:
798569-33-2
Category:
Biologically Active Peptides

reference

  1. D.E. Jones and C.L. Bevins, J. Biol. Chem., 267, 23216 (1992). (Original; Human Defensin-5)
  2. E.M. Porter, M.A. Poles, J.S. Lee, J. Naitoh, C.L. Bevins, amd T. Ganz, FEBS Lett., 434, 272 (1998). (Pharmacol.; Endogenous Form)
  3. N.H. Salzman, D. Ghosh, K.M. Huttner, Y. Paterson, and C.L. Bevins, Nature, 422, 522 (2003). (Pharmacol.)
  4. P. Kelly, R. Feakins, P. Domizio, J. Murphy, C. Bevins, J. Wilson, G. Mcphail, R. Poulsom, and W. Dhaliwal, Clin. Exp. Immunol., 135, 303 (2004). (Histochem.; Location in AIDS Patients)
  5. R.N. Cunliffe, Mol. Immunol., 40, 463 (2003). (Histochem.; α-Defensin in Gastrointestinal Tract)
  6. S. Kubo, K. Tanimura, H. Nishio, N. Chino, T. Teshima, T. Kimura, and Y. Nishiuchi, Int. J. Pept. Res. Ther., 14, 341 (2008). (Chem. Synthesis & Pharmacol.)
  7. R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
  8. M. Zasloff, Nature, 415, 389 (2002). (Review)
  9. T. Hirsch, F. Jacobsen, H.-U. Steinau, and L. Steinstraesser, Protein Pept. Lett., 15, 238 (2008). (Review)
  10. M. Pazgier, X. Li, W. Lu, and J. Lubkowski, Curr. Pharm. Des., 13, 3096 (2007). (Review)

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