α-Defensin-5 (Human)

Documents

Ala-Thr-Cys-Tyr-Cys-Arg-Thr-Gly-Arg-Cys-Ala-Thr-Arg-Glu-Ser-Leu-Ser-Gly-Val-Cys-Glu-Ile-Ser-Gly-Arg-Leu-Tyr-Arg-Leu-Cys-Cys-Arg (Disulfide bonds between Cys³-Cys³¹, Cys⁵-Cys²⁰, and Cys¹⁰-Cys³⁰)
: (M.W. 3582.1) C₁₄₄H₂₃₈N₅₀O₄₅S₆
: Antimicrobial Peptide in Paneth Cells

Package	Price(Yen)	Availability
Vial 0.1 mg	22,000	Ships within 1-3 business days
Bulk Request

Solubility: H₂O (0.1 mM)

D.E. Jones and C.L. Bevins, J. Biol. Chem., 267, 23216 (1992). (Original; Human Defensin-5)
E.M. Porter, M.A. Poles, J.S. Lee, J. Naitoh, C.L. Bevins, amd T. Ganz, FEBS Lett., 434, 272 (1998). (Pharmacol.; Endogenous Form)
N.H. Salzman, D. Ghosh, K.M. Huttner, Y. Paterson, and C.L. Bevins, Nature, 422, 522 (2003). (Pharmacol.)
P. Kelly, R. Feakins, P. Domizio, J. Murphy, C. Bevins, J. Wilson, G. Mcphail, R. Poulsom, and W. Dhaliwal, Clin. Exp. Immunol., 135, 303 (2004). (Histochem.; Location in AIDS Patients)
R.N. Cunliffe, Mol. Immunol., 40, 463 (2003). (Histochem.; α-Defensin in Gastrointestinal Tract)
S. Kubo, K. Tanimura, H. Nishio, N. Chino, T. Teshima, T. Kimura, and Y. Nishiuchi, Int. J. Pept. Res. Ther., 14, 341 (2008). (Chem. Synthesis & Pharmacol.)
R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
M. Zasloff, Nature, 415, 389 (2002). (Review)
T. Hirsch, F. Jacobsen, H.-U. Steinau, and L. Steinstraesser, Protein Pept. Lett., 15, 238 (2008). (Review)
M. Pazgier, X. Li, W. Lu, and J. Lubkowski, Curr. Pharm. Des., 13, 3096 (2007). (Review)
Y. Lai and R.L. Gallo, Trends Immunol., 30, 131 (2009). (Review)

Data Sheet