Lactacystin

Code:
4368-v
Name:
Lactacystin
N-Acetyl-S-{(2R,3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxopyrrolidine-2-carbonyl}-L-cysteine
(M.W. 376.43) C15H24N2O7S
Inhibitor for Proteasome
Package Price(Yen) Availability Quantity  
Vial 0.2 mg 20,000 Ships within
1-3 business days
バルク見積もり

main

Other Name:
ラクタシスチン
Storage:
-20 ℃
Production:
Microbial Product

Solubility: H2O (1 mM)

more information

Structure:
構造図Lactacystin
Category:
Enzyme Inhibitors

reference

  1. S. Omura, T. Fujimoto, K. Otoguro, K. Matsuzaki, R. Moriguchi, H. Tanaka, and Y. Sasaki, J. Antibiotics, 44, 113 (1991). (Original)
  2. S. Omura, K. Matsuzaki, T. Fujimoto, K. Kosuge, T. Furuya, S. Fujita, and A. Nakagawa, J. Antibiotics, 44, 117 (1991). (Original; Chem. Structure)
  3. G. Fenteany, R.F. Standaert, W.S. Lane, S. Choi, E.J. Corey, and S.L. Schreiber, Science, 268, 726 (1995). (Biochem.; Proteasome Inhibition)
  4. S. Imajoh-Ohmi, T. Kawaguchi, S. Sugiyama, K. Tanaka, S. Omura, and H. Kikuchi, Biochem. Biophys. Res. Commun., 217, 1070 (1995). (Biochem.; Apoptotic Effect)
  5. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).

関連書類

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