β-Defensin-2 (Human)
- Code:
- 4338-s
- Name:
- β-Defensin-2 (Human)
- hBD-2
- Gly-Ile-Gly-Asp-Pro-Val-Thr-Cys-Leu-Lys-Ser-Gly-Ala-Ile-Cys-His-Pro-Val-Phe-Cys-Pro-Arg-Arg-Tyr-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Leu-Pro-Gly-Thr-Lys-Cys-Cys-Lys-Lys-Pro (Disulfide bonds between Cys8-Cys37, Cys15-Cys30, and Cys20-Cys38)
- (M.W. 4328.2) C188H305N55O50S6
- Antimicrobial Peptide Specific for Gram-Negative Bacteria/Also Effective for Candida albicans
- main
- more information
- reference
main
- Purity:
- ≧99.0% (HPLC)
- Other Name:
- BD-2 (human)
- β-デフェンシン-2
- Storage:
- -20 ℃
- Production:
- Synthetic Product
Solubility: H2O (0.1 mM)
more information
- Category:
- Biologically Active Peptides
reference
- J. Harder, J. Bartels, E. Christophers, and J.-M. Schröder, Nature, 387, 861 (1997). (Original)
- T. Hiratsuka, M. Nakazato, Y. Date, J. Ashitani, T. Minematsu, N. Chino, and S. Matsukura, Biochem. Biophys. Res. Commun., 249, 943 (1998). (Pharmacol.)
- D.M. Hoover, K.R. Rajashankar, R. Blumenthal, A. Puri., J.J. Oppenheim, O. Chertov, and J. Lubkowski, J. Biol. Chem., 275, 32911 (2000). (S-S Bond)
- T. Hiratsuka, H. Mukae, H. Iiboshi, J. Ashitani, K. Nabeshima, T. Minematsu, N. Chino, T. Ihi, S. Kohno, and M. Nakazato, Thorax, 58, 425 (2003). (Pharmacol.; Activity against Pseudomonas aeruginosa)
- S. Yanagi, J.-i. Ashitani, H. Ishimoto, Y. Date, H.Mukae, N. Chino, and M. Nakazato, Respiratory Res., 6, 130 (2005). (Pharmacol. & Immunohistochem.)
- N. Chino, S. Kubo, H. Nishio, Y. Nishiuchi, M. Nakazato, and T. Kimura, Int. J. Pept. Res. Ther., 12, 203 (2006). (Chem. Synthesis & Pharmacol.)
- R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
- M. Zasloff, Nature, 415, 389 (2002). (Review)
- T. Hirsch, F. Jacobsen, H.-U. Steinau, and L. Steinstraesser, Protein Pept. Lett., 15, 238 (2008). (Review)
- M. Pazgier, X. Li, W. Lu, and J. Lubkowski, Curr. Pharm. Des., 13, 3096 (2007). (Review)
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