β-Defensin-2 (Human)

Code:
4338-s
Name:
β-Defensin-2 (Human)
hBD-2
Gly-Ile-Gly-Asp-Pro-Val-Thr-Cys-Leu-Lys-Ser-Gly-Ala-Ile-Cys-His-Pro-Val-Phe-Cys-Pro-Arg-Arg-Tyr-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Leu-Pro-Gly-Thr-Lys-Cys-Cys-Lys-Lys-Pro (Disulfide bonds between Cys8-Cys37, Cys15-Cys30, and Cys20-Cys38)
(M.W. 4328.2) C188H305N55O50S6
Antimicrobial Peptide Specific for Gram-Negative Bacteria/Also Effective for Candida albicans
Package Price(Yen) Availability Quantity  
Vial 0.1 mg 23,000 Ships within
1-3 business days

main

Purity:
≧99.0% (HPLC)
Other Name:
BD-2 (human)
β-デフェンシン-2
Storage:
-20 ℃
Production:
Synthetic Product

more information

CAS Registry Number:
372146-20-8
Category:
Biologically Active Peptides

reference

  1. J. Harder, J. Bartels, E. Christophers, and J.-M. Schröder, Nature, 387, 861 (1997). (Original)
  2. T. Hiratsuka, M. Nakazato, Y. Date, J. Ashitani, T. Minematsu, N. Chino, and S. Matsukura, Biochem. Biophys. Res. Commun., 249, 943 (1998). (Pharmacol.)
  3. D.M. Hoover, K.R. Rajashankar, R. Blumenthal, A. Puri., J.J. Oppenheim, O. Chertov, and J. Lubkowski, J. Biol. Chem., 275, 32911 (2000). (S-S Bond)
  4. T. Hiratsuka, H. Mukae, H. Iiboshi, J. Ashitani, K. Nabeshima, T. Minematsu, N. Chino, T. Ihi, S. Kohno, and M. Nakazato, Thorax, 58, 425 (2003). (Pharmacol.; Activity against Pseudomonas aeruginosa)
  5. S. Yanagi, J.-i. Ashitani, H. Ishimoto, Y. Date, H.Mukae, N. Chino, and M. Nakazato, Respiratory Res., 6, 130 (2005). (Pharmacol. & Immunohistochem.)
  6. N. Chino, S. Kubo, H. Nishio, Y. Nishiuchi, M. Nakazato, and T. Kimura, Int. J. Pept. Res. Ther., 12, 203 (2006). (Chem. Synthesis & Pharmacol.)
  7. R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
  8. M. Zasloff, Nature, 415, 389 (2002). (Review)
  9. T. Hirsch, F. Jacobsen, H.-U. Steinau, and L. Steinstraesser, Protein Pept. Lett., 15, 238 (2008). (Review)
  10. M. Pazgier, X. Li, W. Lu, and J. Lubkowski, Curr. Pharm. Des., 13, 3096 (2007). (Review)

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