β-Defensin-2 (Human)

Documents

Gly-Ile-Gly-Asp-Pro-Val-Thr-Cys-Leu-Lys-Ser-Gly-Ala-Ile-Cys-His-Pro-Val-Phe-Cys-Pro-Arg-Arg-Tyr-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Leu-Pro-Gly-Thr-Lys-Cys-Cys-Lys-Lys-Pro (Disulfide bonds between Cys⁸-Cys³⁷, Cys¹⁵-Cys³⁰, and Cys²⁰-Cys³⁸)
: (M.W. 4328.2) C₁₈₈H₃₀₅N₅₅O₅₀S₆
: Antimicrobial Peptide Specific for Gram-Negative Bacteria/Also Effective for Candida albicans

Package	Price(Yen)	Availability
Vial 0.1 mg	23,000	Ships within 1-3 business days
Bulk Request

Solubility: H₂O (0.1 mM)

J. Harder, J. Bartels, E. Christophers, and J.-M. Schröder, Nature, 387, 861 (1997). (Original)
T. Hiratsuka, M. Nakazato, Y. Date, J. Ashitani, T. Minematsu, N. Chino, and S. Matsukura, Biochem. Biophys. Res. Commun., 249, 943 (1998). (Pharmacol.)
D.M. Hoover, K.R. Rajashankar, R. Blumenthal, A. Puri., J.J. Oppenheim, O. Chertov, and J. Lubkowski, J. Biol. Chem., 275, 32911 (2000). (S-S Bond)
T. Hiratsuka, H. Mukae, H. Iiboshi, J. Ashitani, K. Nabeshima, T. Minematsu, N. Chino, T. Ihi, S. Kohno, and M. Nakazato, Thorax, 58, 425 (2003). (Pharmacol.; Activity against Pseudomonas aeruginosa)
S. Yanagi, J.-i. Ashitani, H. Ishimoto, Y. Date, H.Mukae, N. Chino, and M. Nakazato, Respiratory Res., 6, 130 (2005). (Pharmacol. & Immunohistochem.)
N. Chino, S. Kubo, H. Nishio, Y. Nishiuchi, M. Nakazato, and T. Kimura, Int. J. Pept. Res. Ther., 12, 203 (2006). (Chem. Synthesis & Pharmacol.)
R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
M. Zasloff, Nature, 415, 389 (2002). (Review)
T. Hirsch, F. Jacobsen, H.-U. Steinau, and L. Steinstraesser, Protein Pept. Lett., 15, 238 (2008). (Review)
M. Pazgier, X. Li, W. Lu, and J. Lubkowski, Curr. Pharm. Des., 13, 3096 (2007). (Review)
Y. Lai and R.L. Gallo, Trends Immunol., 30, 131 (2009). (Review)

Data Sheet