Dendrotoxin I
- Code:
- 4330-s
- Name:
- Dendrotoxin I
- Pyr-Pro-Leu-Arg-Lys-Leu-Cys-Ile-Leu-His-Arg-Asp-Pro-Gly-Arg-Cys-Tyr-Gln-Lys-Ile-Pro-Ala-Phe-Tyr-Tyr-Asn-Gln-Lys-Lys-Lys-Gln-Cys-Glu-Gly-Phe-Thr-Trp-Ser-Gly-Cys-Gly-Gly-Asn-Ser-Asn-Arg-Phe-Lys-Thr-Ile-Glu-Glu-Cys-Arg-Arg-Thr-Cys-Ile-Arg-Lys (Disulfide bonds between Cys7-Cys57, Cys16-Cys40, and Cys32-Cys53)
- (M.W. 7133.2) C312H487N97O84S6
- Voltage-dependent K+ Channel Blocker
- main
- more information
- reference
main
- Purity:
- ≧99.0% (HPLC)
- Storage:
- -20 ℃
- Source:
- Black mamba, Dendroaspis polylepis polylepis
- Production:
- Synthetic Product
Solubility: 0.1% AcOH (10 μM)
more information
- Category:
- Biologically Active Peptides
reference
- D.J. Strydom, Nature New Biol., 243, 88 (1973). (Original)
- J.-N. Bidard, C. Mourre, and M. Lazdunski, Biochem. Biophys. Res. Commun., 143, 383 (1987). (Pharmacol.)
- A.L. Harvey, D.L. Marshall, F.A. De-Allie, and P.N. Strong, Biochem. Biophys. Res. Commun., 163, 394 (1989). (Pharmacol.)
- H. Nishio, T. Inui, Y. Nishiuchi, C.L.C. De Medeiros, E.G. Rowan, A.L. Harvey, E. Katoh, T. Yamazaki, T. Kimura, and S. Sakakibara, J. Pept. Res., 51, 355 (1998). (Chem. Synthesis & Correction of Sequence; Asp12)
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