E-64-d

Code:
4321-v
Name:
E-64-d
[(2S,3S)-3-Ethoxycarbonyloxirane-2-carbonyl]-L-leucine (3-methylbutyl)amide
(M.W. 342.43) C17H30N2O5
Inhibitor for Thiol Protease (Cathepsin B/H/L, Calpain)
Membrane Permeable Analog of E-64-c
Package Price(Yen) Availability Quantity  
Vial 5 mg 10,000 Ships within
1-3 business days

main

Purity:
≧98.0% (HPLC)
Other Name:
E-64d
L-trans-Epoxysuccinyl-Leu-3-methylbutylamide-ethyl ester
Aloxistatin
Loxistatin
(2S,3S)-trans-エポキシスクシニル-L-ロイシルアミド-3-メチルブタン エチルエステル
Storage:
-20 ℃
Production:
Synthetic Product

more information

Structure:
構造図E-64-d
CAS Registry Number:
88321-09-9
Category:
Enzyme Inhibitors

reference

  1. M. Tamai, K. Matsumoto, S. Omura, I. Koyama, Y. Ozawa, and K. Hanada, J. Pharmacobio-Dyn., 9, 672 (1986). (Original)
  2. M. Tamai, C. Yokoo, M. Murata, K. Oguma, K. Sota, E. Sato, and Y. Kanaoka, Chem. Pharm. Bull., 35, 1098 (1987). (Chem. Synthesis & Biochem.)
  3. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).

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