4321-v E-64-d
- Code:
- 4321-v
- Name:
- E-64-d
- [(2S,3S)-3-Ethoxycarbonyloxirane-2-carbonyl]-L-leucine (3-methylbutyl)amide
- (M.W. 342.43) C17H30N2O5
- Inhibitor for Thiol Protease (Cathepsin B/H/L, Calpain)
Membrane Permeable Analog of E-64-c
Package | Price(Yen) |
---|---|
Vial 5 mg | 10,000 |
- main
- more information
- reference
main
- Purity:
- ≧98.0% (HPLC)
- Other Name:
- E-64d
- L-trans-Epoxysuccinyl-Leu-3-methylbutylamide-ethyl ester
- Aloxistatin
- Loxistatin
- (2S,3S)-trans-エポキシスクシニル-L-ロイシルアミド-3-メチルブタン エチルエステル
- Storage:
- -20 ℃
- Production:
- Synthetic Product
Solubility: DMSO (10 mM)
more information
- Structure:
- Category:
- Enzyme Inhibitors
reference
- M. Tamai, K. Matsumoto, S. Omura, I. Koyama, Y. Ozawa, and K. Hanada, J. Pharmacobio-Dyn., 9, 672 (1986). (Original)
- M. Tamai, C. Yokoo, M. Murata, K. Oguma, K. Sota, E. Sato, and Y. Kanaoka, Chem. Pharm. Bull., 35, 1098 (1987). (Chem. Synthesis & Biochem.)
- D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).