E-64-c
- Code:
- 4320-v
- Name:
- E-64-c
- [(2S,3S)-3-Carboxyoxirane-2-carbonyl]-L-leucine (3-methylbutyl)amide
- (M.W. 314.38) C15H26N2O5
- Inhibitor for Thiol Protease (Cathepsin B/H/L and Calpain)
- main
- more information
- reference
main
- Purity:
- ≧98.0% (HPLC)
- Storage:
- -20 ℃
- Production:
- Synthetic Product
Solubility: DMSO (10 mM)
more information
- Structure:
- Category:
- Enzyme Inhibitors
reference
- S. Hashida, T. Towatari, E. Kominami, and N. Katunuma, J. Biochem., 88, 1805 (1980). (Original; IC50)
- M. Tamai, K. Hanada, T. Adachi, K. Oguma, K. Kashiwagi, S. Omura, and M. Ohzeki, J. Biochem., 90, 255 (1981). (Chem. Structure & Biochem.)
- A.J. Barrett, A.A. Kembhavi, M.A. Brown, H. Kirschke, C.G. Knight, M. Tamai, and K. Hanada, Biochem. J., 201, 189 (1982). (Biochem.)
- K. Suzuki, J. Biochem., 93, 1305 (1983). (Biochem.)
- D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).
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