4320-v E-64-c

Code:
4320-v
Name:
E-64-c
[(2S,3S)-3-Carboxyoxirane-2-carbonyl]-L-leucine (3-methylbutyl)amide
(M.W. 314.38) C15H26N2O5
Inhibitor for Thiol Protease (Cathepsin B/H/L and Calpain)
Package Price(Yen)
Vial 5 mg 10,000

main

Purity:
≧98.0% (HPLC)
Storage:
-20 ℃
Production:
Synthetic Product

Solubility: DMSO (10 mM)

more information

Structure:
構造図E-64-c
CAS Registry Number:
76684-89-4
Category:
Enzyme Inhibitors

reference

  1. S. Hashida, T. Towatari, E. Kominami, and N. Katunuma, J. Biochem., 88, 1805 (1980). (Original; IC50)
  2. M. Tamai, K. Hanada, T. Adachi, K. Oguma, K. Kashiwagi, S. Omura, and M. Ohzeki, J. Biochem., 90, 255 (1981). (Chem. Structure & Biochem.)
  3. A.J. Barrett, A.A. Kembhavi, M.A. Brown, H. Kirschke, C.G. Knight, M. Tamai, and K. Hanada, Biochem. J., 201, 189 (1982). (Biochem.)
  4. K. Suzuki, J. Biochem., 93, 1305 (1983). (Biochem.)
  5. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).