ω-Agatoxin IVA
- Code:
- 4256-s
- Name:
- ω-Agatoxin IVA
- ω-Aga-IVA
- Lys-Lys-Lys-Cys-Ile-Ala-Lys-Asp-Tyr-Gly-Arg-Cys-Lys-Trp-Gly-Gly-Thr-Pro-Cys-Cys-Arg-Gly-Arg-Gly-Cys-Ile-Cys-Ser-Ile-Met-Gly-Thr-Asn-Cys-Glu-Cys-Lys-Pro-Arg-Leu-Ile-Met-Glu-Gly-Leu-Gly-Leu-Ala (Disulfide bonds between Cys4-Cys20, Cys12-Cys25, Cys19-Cys36, and Cys27-Cys34)
- (M.W. 5202.2) C217H360N68O60S10
- P-type Ca2+ Channel Selective Blocker
- main
- more information
- reference
main
- Purity:
- ≧97.0% (HPLC)
- Other Name:
- ω-アガトキシンIVA
- Storage:
- -20 ℃
- Source:
- Funnel Web Spider, Agelenopsis aperta
- Production:
- Synthetic Product
Solubility: H2O (0.1 mM)
more information
- Category:
- Biologically Active Peptides
reference
- I.M. Mintz, V.J. Venema, K.M. Swiderek, T.D. Lee, B.P. Bean, and M.E. Adams, Nature, 355, 827 (1992). (Original)
- T.J. Turner, M.E. Adams, and K. Dunlap, Science, 258, 310 (1992). (Pharmacol.)
- H. Nishio, K.Y. Kumagaye, S. Kubo, Y.-N. Chen, A. Momiyama, T. Takahashi, T. Kimura, and S. Sakakibara, Biochem. Biophys. Res. Commun., 196, 1447 (1993). (Chem. Synthesis & Biological Activity)
- B.M. Olivera, G.P. Miljanich, J. Ramachandran, and M.E. Adams, Annu. Rev. Biochem., 63, 823 (1994). (Review)
- O.D. Uchitel, Toxicon, 35, 1161 (1997). (Review)
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