4256-s ω-Agatoxin IVA

Code:
4256-s
Name:
ω-Agatoxin IVA
ω-Aga-IVA
Lys-Lys-Lys-Cys-Ile-Ala-Lys-Asp-Tyr-Gly-Arg-Cys-Lys-Trp-Gly-Gly-Thr-Pro-Cys-Cys-Arg-Gly-Arg-Gly-Cys-Ile-Cys-Ser-Ile-Met-Gly-Thr-Asn-Cys-Glu-Cys-Lys-Pro-Arg-Leu-Ile-Met-Glu-Gly-Leu-Gly-Leu-Ala (Disulfide bonds between Cys4-Cys20, Cys12-Cys25, Cys19-Cys36, and Cys27-Cys34)
(M.W. 5202.2) C217H360N68O60S10
P-type Ca2+ Channel Selective Blocker
Package Price(Yen)
Vial 0.1 mg 30,000

main

Purity:
≧97.0% (HPLC)
Other Name:
ω-アガトキシンIVA
Storage:
-20 ℃
Source:
Funnel Web Spider, Agelenopsis aperta
Production:
Synthetic Product

Solubility: H2O (0.1 mM)

more information

CAS Registry Number:
145017-83-0
Category:
Biologically Active Peptides

reference

  1. I.M. Mintz, V.J. Venema, K.M. Swiderek, T.D. Lee, B.P. Bean, and M.E. Adams, Nature, 355, 827 (1992). (Original)
  2. T.J. Turner, M.E. Adams, and K. Dunlap, Science, 258, 310 (1992). (Pharmacol.)
  3. H. Nishio, K.Y. Kumagaye, S. Kubo, Y.-N. Chen, A. Momiyama, T. Takahashi, T. Kimura, and S. Sakakibara, Biochem. Biophys. Res. Commun., 196, 1447 (1993). (Chem. Synthesis & Biological Activity)
  4. B.M. Olivera, G.P. Miljanich, J. Ramachandran, and M.E. Adams, Annu. Rev. Biochem., 63, 823 (1994). (Review)
  5. O.D. Uchitel, Toxicon, 35, 1161 (1997). (Review)