Calciseptine
- Code:
- 4255-s
- Name:
- Calciseptine
- Arg-Ile-Cys-Tyr-Ile-His-Lys-Ala-Ser-Leu-Pro-Arg-Ala-Thr-Lys-Thr-Cys-Val-Glu-Asn-Thr-Cys-Tyr-Lys-Met-Phe-Ile-Arg-Thr-Gln-Arg-Glu-Tyr-Ile-Ser-Glu-Arg-Gly-Cys-Gly-Cys-Pro-Thr-Ala-Met-Trp-Pro-Tyr-Gln-Thr-Glu-Cys-Cys-Lys-Gly-Asp-Arg-Cys-Asn-Lys (Disulfide bonds between Cys3-Cys22, Cys17-Cys39, Cys41-Cys52, and Cys53-Cys58)
- (M.W. 7036.1) C299H468N90O87S10
- L-type Ca2+ Channel Blocker
- main
- more information
- reference
main
- Purity:
- ≧97.0% (HPLC)
- Storage:
- -20 ℃
- Source:
- Black mamba, Dendroaspis polylepis polylepis
- Production:
- Synthetic Product
Solubility: H2O (10 μM)
more information
- Category:
- Biologically Active Peptides
reference
- J.R. De Weille, H. Schweitz, P. Maes, A. Tartar, and M. Lazdunski, Proc. Natl. Acad. Sci. USA, 88, 2437 (1991). (Original)
- H. Kuroda, Y.-N. Chen, T.X. Watanabe, T. Kimura, and S. Sakakibara, Pept. Res., 5, 265 (1992). (Chem. Synthesis)
- T.X. Watanabe, Y. Itahara, H. Kuroda, Y.-N. Chen, T. Kimura, and S. Sakakibara, Jpn. J. Pharmacol., 68, 305 (1995). (Pharmacol.)
- N. Teramoto, R. Ogata, K. Okabe, A. Kameyama, M. Kameyama, T.X. Watanabe, H. Kuriyama, and K. Kitamura, Pflügers Arch., 432, 462 (1996). (Pharmacol.)
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