4255-s Calciseptine

Code:
4255-s
Name:
Calciseptine
Arg-Ile-Cys-Tyr-Ile-His-Lys-Ala-Ser-Leu-Pro-Arg-Ala-Thr-Lys-Thr-Cys-Val-Glu-Asn-Thr-Cys-Tyr-Lys-Met-Phe-Ile-Arg-Thr-Gln-Arg-Glu-Tyr-Ile-Ser-Glu-Arg-Gly-Cys-Gly-Cys-Pro-Thr-Ala-Met-Trp-Pro-Tyr-Gln-Thr-Glu-Cys-Cys-Lys-Gly-Asp-Arg-Cys-Asn-Lys (Disulfide bonds between Cys3-Cys22, Cys17-Cys39, Cys41-Cys52, and Cys53-Cys58)
(M.W. 7036.1) C299H468N90O87S10
L-type Ca2+ Channel Blocker
Package Price(Yen)
Vial 0.1 mg 30,000

main

Purity:
≧97.0% (HPLC)
Storage:
-20 ℃
Source:
Black mamba, Dendroaspis polylepis polylepis
Production:
Synthetic Product

Solubility: H2O (10 μM)

more information

CAS Registry Number:
134710-25-1
Category:
Biologically Active Peptides

reference

  1. J.R. De Weille, H. Schweitz, P. Maes, A. Tartar, and M. Lazdunski, Proc. Natl. Acad. Sci. USA, 88, 2437 (1991). (Original)
  2. H. Kuroda, Y.-N. Chen, T.X. Watanabe, T. Kimura, and S. Sakakibara, Pept. Res., 5, 265 (1992). (Chem. Synthesis)
  3. T.X. Watanabe, Y. Itahara, H. Kuroda, Y.-N. Chen, T. Kimura, and S. Sakakibara, Jpn. J. Pharmacol., 68, 305 (1995). (Pharmacol.)
  4. N. Teramoto, R. Ogata, K. Okabe, A. Kameyama, M. Kameyama, T.X. Watanabe, H. Kuriyama, and K. Kitamura, Pflügers Arch., 432, 462 (1996). (Pharmacol.)