Elafin (Human)
- Code:
- 4243-v
- Name:
- Elafin (Human)
- Ala-Gln-Glu-Pro-Val-Lys-Gly-Pro-Val-Ser-Thr-Lys-Pro-Gly-Ser-Cys-Pro-Ile-Ile-Leu-Ile-Arg-Cys-Ala-Met-Leu-Asn-Pro-Pro-Asn-Arg-Cys-Leu-Lys-Asp-Thr-Asp-Cys-Pro-Gly-Ile-Lys-Lys-Cys-Cys-Glu-Gly-Ser-Cys-Gly-Met-Ala-Cys-Phe-Val-Pro-Gln (Disulfide bonds between Cys16-Cys45, Cys23-Cys49, Cys32-Cys44, and Cys38-Cys53)
- (M.W. 5999.1) C254H416N72O75S10
- Elastase-Specific Inhibitor from Human Skin / Innate Immune Factor
- main
- more information
- reference
main
- Purity:
- ≧97.0% (HPLC)
- Storage:
- -20 ℃
Solubility: H2O (10 μM)
more information
- Category:
- Biologically Active Peptides
reference
- O. Wiedow, J.-M. Schröder, H. Gregory, J.A. Young, and E. Christophers, J. Biol. Chem., 265, 14791 (1990). (Original)
- O. Wiedow, J.-M. Schröder, H. Gregory, J.A. Young, and E. Christophers, J. Biol. Chem., 266, 3356 (1991). (Correction of Sequence)
- M. Tsunemi, H. Kato, Y. Nishiuchi, S. Kumagaye, and S. Sakakibara, Biochem. Biophys. Res. Commun., 185, 967 (1992). (Chem. Synthesis & Biochem.)
- M. Tsunemi, Y. Matsuura, S. Sakakibara, and Y. Katsube, Biochemistry, 35, 11570 (1996). (Biochem; Crystal Structure of Elafin-Pancreatic Elastase)
- L. Marischen, D. Wesch, J.-M. Schröder, O. Wiedow, and D. Kabelitz, Scand. J. Immunol., 70, 547 (2009). (Pharmacol.)
- S.M. Iqbal, T.B. Ball, P. Levinson, L. Maranan, W. Jaoko, C. Wachihi, B.J. Pak, V.N. Podust, K. Broliden, T. Hirbod, R. Kaul, and F.A. Plummer, AIDS, 23, 1669 (2009). (Pharmacol.)
- D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).
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