Elafin (Human)

Code:
4243-v
Name:
Elafin (Human)
Ala-Gln-Glu-Pro-Val-Lys-Gly-Pro-Val-Ser-Thr-Lys-Pro-Gly-Ser-Cys-Pro-Ile-Ile-Leu-Ile-Arg-Cys-Ala-Met-Leu-Asn-Pro-Pro-Asn-Arg-Cys-Leu-Lys-Asp-Thr-Asp-Cys-Pro-Gly-Ile-Lys-Lys-Cys-Cys-Glu-Gly-Ser-Cys-Gly-Met-Ala-Cys-Phe-Val-Pro-Gln (Disulfide bonds between Cys16-Cys45, Cys23-Cys49, Cys32-Cys44, and Cys38-Cys53)
(M.W. 5999.1) C254H416N72O75S10
Elastase-Specific Inhibitor from Human Skin / Innate Immune Factor
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Purity:
≧97.0% (HPLC)
Storage:
-20 ℃

Solubility: H2O (10 μM)

more information

Category:
Biologically Active Peptides

reference

  1. O. Wiedow, J.-M. Schröder, H. Gregory, J.A. Young, and E. Christophers, J. Biol. Chem., 265, 14791 (1990). (Original)
  2. O. Wiedow, J.-M. Schröder, H. Gregory, J.A. Young, and E. Christophers, J. Biol. Chem., 266, 3356 (1991). (Correction of Sequence)
  3. M. Tsunemi, H. Kato, Y. Nishiuchi, S. Kumagaye, and S. Sakakibara, Biochem. Biophys. Res. Commun., 185, 967 (1992). (Chem. Synthesis & Biochem.)
  4. M. Tsunemi, Y. Matsuura, S. Sakakibara, and Y. Katsube, Biochemistry, 35, 11570 (1996). (Biochem; Crystal Structure of Elafin-Pancreatic Elastase)
  5. L. Marischen, D. Wesch, J.-M. Schröder, O. Wiedow, and D. Kabelitz, Scand. J. Immunol., 70, 547 (2009). (Pharmacol.)
  6. S.M. Iqbal, T.B. Ball, P. Levinson, L. Maranan, W. Jaoko, C. Wachihi, B.J. Pak, V.N. Podust, K. Broliden, T. Hirbod, R. Kaul, and F.A. Plummer, AIDS, 23, 1669 (2009). (Pharmacol.)
  7. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).

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