E-64
- Code:
- 4096-v
- Name:
- E-64
- [(2S,3S)-3-Carboxyoxirane-2-carbonyl]-L-leucine (4-guanidinobutyl)amide
- (M.W. 357.41) C15H27N5O5
- Inhibitor for Thiol Proteases
- main
- more information
- reference
main
- Purity:
- ≧98.0% (HPLC)
- Other Name:
- L-trans-Epoxysuccinyl-Leu-4-guanidinobutylamide
- L-trans-Epoxysuccinyl-Leu-agmatine
- Storage:
- -20 ℃
- Production:
- Synthetic Product
Solubility: H2O (1 mM)
more information
- Structure:
- Category:
- Enzyme Inhibitors
reference
- K. Hanada, M. Tamai, M. Yamagishi, S. Ohmura, J. Sawada, and I. Tanaka, Agric. Biol. Chem., 42, 523 (1978). (Original)
- K. Hanada, M. Tamai, S. Ohmura, J. Sawada, T. Seki and I. Tanaka, Agric. Biol. Chem., 42, 529 (1978). (Structure & Chem. Synthesis)
- Y. Shoji-Kasai, M. Senshu, S. Iwashita, and K. Imahori, Proc. Natl. Acad. Sci. USA, 85, 146 (1988). (Pharmacol.)
- D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).
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