E-64

Code:
4096-v
Name:
E-64
[(2S,3S)-3-Carboxyoxirane-2-carbonyl]-L-leucine (4-guanidinobutyl)amide
(M.W. 357.41) C15H27N5O5
Inhibitor for Thiol Proteases
Package Price(Yen) Availability
Vial 0.5 mg 5,000 Ships within
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Purity:
≧98.0% (HPLC)
Other Name:
L-trans-Epoxysuccinyl-Leu-4-guanidinobutylamide
L-trans-Epoxysuccinyl-Leu-agmatine
Storage:
-20 ℃
Production:
Synthetic Product

Solubility: H2O (1 mM)

more information

Structure:
structure of E-64
Category:
Enzyme Inhibitors

reference

  1. K. Hanada, M. Tamai, M. Yamagishi, S. Ohmura, J. Sawada, and I. Tanaka, Agric. Biol. Chem., 42, 523 (1978). (Original)
  2. K. Hanada, M. Tamai, S. Ohmura, J. Sawada, T. Seki and I. Tanaka, Agric. Biol. Chem., 42, 529 (1978). (Structure & Chem. Synthesis)
  3. Y. Shoji-Kasai, M. Senshu, S. Iwashita, and K. Imahori, Proc. Natl. Acad. Sci. USA, 85, 146 (1988). (Pharmacol.)
  4. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).

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