Z-Arg-Leu-Arg-Gly-Gly-MCA
- Code:
- 3252-v
- Name:
- Z-Arg-Leu-Arg-Gly-Gly-MCA
- Benzyloxycarbonyl-L-arginyl-L-leucyl-L-arginylglycylglycine 4-methylcoumaryl-7-amide
- (M.W. 848.95) C40H56N12O9
- Fluorogenic Substrate for Isopeptidase T and Coronavirus (CoV) PLpro
- main
- more information
- reference
main
- Purity:
- ≧98.0% (HPLC)
- Storage:
- -20 ℃
Solubility: 50% DMSO (2 mM)
more information
- Category:
- Enzyme Substrates and Related Peptides
reference
- R.L. Stein, Z.J. Chen, and F. Melandri, Biochemistry, 34, 12616 (1995). (Original; Substrate for Isopeptidase T)
- Y.M. Baez-Santos, A.M. Mielech, X. Deng, S. Baker, and A.D. Mesecar, J. Virol., 88, 12511 (2014). (Substrate for CoV PLpro)
- E. Smith, M.E. Davis-Gardner, R.D. Garcia-Ordonez, T.-T.Nguyen, M. Hull, E. Chen, P. Baillargeon, L. Scampavia, T.Strutzenberg, P. Griffin, M. Farzan, and T.P. Spicer, SLASDiscov., (2020). (Substrate for SARS-CoV-2 PLpro Enzymatic Assay)
- A.K. Ghosh, M. Brindisi, D. Shahabi, M.E. Chapman, and A.D. Mesecar, ChemMedChem, 15, 907 (2020). (Review)
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