Z-Arg-Leu-Arg-Gly-Gly-MCA

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Benzyloxycarbonyl-L-arginyl-L-leucyl-L-arginylglycylglycine 4-methylcoumaryl-7-amide
: (M.W. 848.95) C₄₀H₅₆N₁₂O₉
: Fluorogenic Substrate for Isopeptidase T and Coronavirus (CoV) PL^pro

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Solubility: 50% DMSO (2 mM)

R.L. Stein, Z.J. Chen, and F. Melandri, Biochemistry, 34, 12616 (1995). (Original; Substrate for Isopeptidase T)
Y.M. Baez-Santos, A.M. Mielech, X. Deng, S. Baker, and A.D. Mesecar, J. Virol., 88, 12511 (2014). (Substrate for CoV PL^pro)
E. Smith, M.E. Davis-Gardner, R.D. Garcia-Ordonez, T.-T.Nguyen, M. Hull, E. Chen, P. Baillargeon, L. Scampavia, T.Strutzenberg, P. Griffin, M. Farzan, and T.P. Spicer, SLASDiscov., (2020). (Substrate for SARS-CoV-2 PL^pro Enzymatic Assay)
A.K. Ghosh, M. Brindisi, D. Shahabi, M.E. Chapman, and A.D. Mesecar, ChemMedChem, 15, 907 (2020). (Review)

Data Sheet