4243-v Elafin (Human)

Code:
4243-v
Name:
Elafin (Human)
Ala-Gln-Glu-Pro-Val-Lys-Gly-Pro-Val-Ser-Thr-Lys-Pro-Gly-Ser-Cys-Pro-Ile-Ile-Leu-Ile-Arg-Cys-Ala-Met-Leu-Asn-Pro-Pro-Asn-Arg-Cys-Leu-Lys-Asp-Thr-Asp-Cys-Pro-Gly-Ile-Lys-Lys-Cys-Cys-Glu-Gly-Ser-Cys-Gly-Met-Ala-Cys-Phe-Val-Pro-Gln (Disulfide bonds between Cys16-Cys45, Cys23-Cys49, Cys32-Cys44, and Cys38-Cys53)
(M.W. 5999.1) C254H416N72O75S10
Elastase-Specific Inhibitor from Human Skin / Innate Immune Factor
Package Price(Yen)
Vial 20 μg 20,000

main

Purity:
≧97.0% (HPLC)
Storage:
-20 ℃

Solubility: H2O (10 μM)

more information

CAS Registry Number:
142191-63-7
Category:
Biologically Active Peptides

reference

  1. O. Wiedow, J.-M. Schröder, H. Gregory, J.A. Young, and E. Christophers, J. Biol. Chem., 265, 14791 (1990). (Original)
  2. O. Wiedow, J.-M. Schröder, H. Gregory, J.A. Young, and E. Christophers, J. Biol. Chem., 266, 3356 (1991). (Correction of Sequence)
  3. M. Tsunemi, H. Kato, Y. Nishiuchi, S. Kumagaye, and S. Sakakibara, Biochem. Biophys. Res. Commun., 185, 967 (1992). (Chem. Synthesis & Biochem.)
  4. M. Tsunemi, Y. Matsuura, S. Sakakibara, and Y. Katsube, Biochemistry, 35, 11570 (1996). (Biochem; Crystal Structure of Elafin-Pancreatic Elastase)
  5. L. Marischen, D. Wesch, J.-M. Schröder, O. Wiedow, and D. Kabelitz, Scand. J. Immunol., 70, 547 (2009). (Pharmacol.)
  6. S.M. Iqbal, T.B. Ball, P. Levinson, L. Maranan, W. Jaoko, C. Wachihi, B.J. Pak, V.N. Podust, K. Broliden, T. Hirbod, R. Kaul, and F.A. Plummer, AIDS, 23, 1669 (2009). (Pharmacol.)
  7. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).