4096-v E-64

Code:
4096-v
Name:
E-64
[(2S,3S)-3-Carboxyoxirane-2-carbonyl]-L-leucine (4-guanidinobutyl)amide
(M.W. 357.41) C15H27N5O5
Inhibitor for Thiol Proteases
Package Price(Yen)
Vial 0.5 mg 5,000

main

Purity:
≧98.0% (HPLC)
Other Name:
L-trans-Epoxysuccinyl-Leu-4-guanidinobutylamide
L-trans-Epoxysuccinyl-Leu-agmatine
Storage:
-20 ℃
Production:
Synthetic Product

Solubility: H2O (1 mM)

more information

Structure:
structure of E-64
CAS Registry Number:
66701-25-5
Category:
Enzyme Inhibitors

reference

  1. K. Hanada, M. Tamai, M. Yamagishi, S. Ohmura, J. Sawada, and I. Tanaka, Agric. Biol. Chem., 42, 523 (1978). (Original)
  2. K. Hanada, M. Tamai, S. Ohmura, J. Sawada, T. Seki and I. Tanaka, Agric. Biol. Chem., 42, 529 (1978). (Structure & Chem. Synthesis)
  3. Y. Shoji-Kasai, M. Senshu, S. Iwashita, and K. Imahori, Proc. Natl. Acad. Sci. USA, 85, 146 (1988). (Pharmacol.)
  4. D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).