3252-v Z-Arg-Leu-Arg-Gly-Gly-MCA

Code:
3252-v
Name:
Z-Arg-Leu-Arg-Gly-Gly-MCA
Benzyloxycarbonyl-L-arginyl-L-leucyl-L-arginylglycylglycine 4-methylcoumaryl-7-amide
(M.W. 848.95) C40H56N12O9
Fluorogenic Substrate for Isopeptidase T and Coronavirus (CoV) PLpro
Package Price(Yen)
Vial 1 mg 10,000

main

Purity:
≧98.0% (HPLC)
Storage:
-20 ℃

Solubility: 50% DMSO (2 mM)

more information

CAS Registry Number:
167698-69-3
Category:
Enzyme Substrates and Related Peptides

reference

  1. R.L. Stein, Z.J. Chen, and F. Melandri, Biochemistry, 34, 12616 (1995). (Original; Substrate for Isopeptidase T)
  2. Y.M. Baez-Santos, A.M. Mielech, X. Deng, S. Baker, and A.D. Mesecar, J. Virol., 88, 12511 (2014). (Substrate for CoV PLpro)
  3. E. Smith, M.E. Davis-Gardner, R.D. Garcia-Ordonez, T.-T.Nguyen, M. Hull, E. Chen, P. Baillargeon, L. Scampavia, T.Strutzenberg, P. Griffin, M. Farzan, and T.P. Spicer, SLASDiscov., (2020). (Substrate for SARS-CoV-2 PLpro Enzymatic Assay)
  4. A.K. Ghosh, M. Brindisi, D. Shahabi, M.E. Chapman, and A.D. Mesecar, ChemMedChem, 15, 907 (2020). (Review)