α-Defensin-4 (Human)
- Code:
- 4431-s
- Name:
- α-Defensin-4 (Human)
- HNP-4 (Human Neutrophil Peptide-4)
- Val-Cys-Ser-Cys-Arg-Leu-Val-Phe-Cys-Arg-Arg-Thr-Glu-Leu-Arg-Val-Gly-Asn-Cys-Leu-Ile-Gly-Gly-Val-Ser-Phe-Thr-Tyr-Cys-Cys-Thr-Arg-Val (Disulfide bonds between Cys2-Cys30, Cys4-Cys19, and Cys9-Cys29)
- (M.W. 3709.4) C157H255N49O43S6
- Antimicrobial Peptide
- main
- more information
- reference
main
- Purity:
- ≧99.0% (HPLC)
- Other Name:
- α-ディフェンシン-4
- α-デフェンシン-4
- Storage:
- -20 ℃
- Production:
- Synthetic Product
Solubility: H2O (0.1 mM)
more information
- Category:
- Biologically Active Peptides
reference
- A. Singh, A. Bateman, Q. Zhu, S. Shimasaki, F. Esch, and S. Solomon, Biochem. Biophys. Res. Commun., 155, 524 (1988). (Original; Primary Structure/Anti-ACTH Activity)
- C.G. Wilde, J.E. Griffith, M.N. Marra, J.L. Snable, and R.W. Scott, J. Biol. Chem., 264, 11200 (1989). (Original; Structure/HNP-4/Antimicrobial Activity)
- Z. Wu, B. Ericksen, K. Tucker, J. Lubkowski, and W. Lu, J. Pept. Res., 64, 118 (2004). (Pharmacol; Antimicrobial Activity)
- B. Ericksen, Z. Wu, W. Lu, and R.I. Lehrer, Antimicrob. Agents Chemother., 49, 269 (2005). (Pharmacol; Antimicrobial Activity)
- Z. Wu, F. Cocchi, D. Gentles, B. Ericksen, J. Lubkowski, A. DeVico, R.I. Lehrer, and W. Lu, FEBS Lett., 579, 162 (2005). (Pharmacol.; HIV-1 Inhibitory Activity)
- G. Wei, E. de Leeuw, M. Pazgier, W. Yuan, G. Zou, J. Wang, B. Ericksen, W.-Y. Lu, R.I. Lehrer, and W. Lu, J. Biol. Chem., 284, 29180 (2009). (Pharmacol.;Iinhibition of Bacillus anthracis Lethal Factor)
- R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
- M. Zasloff, Nature, 415, 389 (2002). (Review)
- T. Hirsch, F. Jacobsen, H.-U. Steinau, and L. Steinstraesser, Protein Pept. Lett., 15, 238 (2008). (Review)
- M. Pazgier, X. Li, W. Lu, and J. Lubkowski, Curr. Pharm. Des., 13, 3096 (2007). (Review)
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