α-Defensin-4 (Human)

Code:
4431-s
Name:
α-Defensin-4 (Human)
HNP-4 (Human Neutrophil Peptide-4)
Val-Cys-Ser-Cys-Arg-Leu-Val-Phe-Cys-Arg-Arg-Thr-Glu-Leu-Arg-Val-Gly-Asn-Cys-Leu-Ile-Gly-Gly-Val-Ser-Phe-Thr-Tyr-Cys-Cys-Thr-Arg-Val (Disulfide bonds between Cys2-Cys30, Cys4-Cys19, and Cys9-Cys29)
(M.W. 3709.4) C157H255N49O43S6
Antimicrobial Peptide
Package Price(Yen) Availability Quantity  
Vial 0.1 mg 22,000 Ships within
1-3 business days

main

Purity:
≧99.0% (HPLC)
Other Name:
α-ディフェンシン-4
α-デフェンシン-4
Storage:
-20 ℃
Production:
Synthetic Product

more information

Category:
Biologically Active Peptides

reference

  1. A. Singh, A. Bateman, Q. Zhu, S. Shimasaki, F. Esch, and S. Solomon, Biochem. Biophys. Res. Commun., 155, 524 (1988). (Original; Primary Structure/Anti-ACTH Activity)
  2. C.G. Wilde, J.E. Griffith, M.N. Marra, J.L. Snable, and R.W. Scott, J. Biol. Chem., 264, 11200 (1989). (Original; Structure/HNP-4/Antimicrobial Activity)
  3. Z. Wu, B. Ericksen, K. Tucker, J. Lubkowski, and W. Lu, J. Pept. Res., 64, 118 (2004). (Pharmacol; Antimicrobial Activity)
  4. B. Ericksen, Z. Wu, W. Lu, and R.I. Lehrer, Antimicrob. Agents Chemother., 49, 269 (2005). (Pharmacol; Antimicrobial Activity)
  5. Z. Wu, F. Cocchi, D. Gentles, B. Ericksen, J. Lubkowski, A. DeVico, R.I. Lehrer, and W. Lu, FEBS Lett., 579, 162 (2005). (Pharmacol.; HIV-1 Inhibitory Activity)
  6. G. Wei, E. de Leeuw, M. Pazgier, W. Yuan, G. Zou, J. Wang, B. Ericksen, W.-Y. Lu, R.I. Lehrer, and W. Lu, J. Biol. Chem., 284, 29180 (2009). (Pharmacol.;Iinhibition of Bacillus anthracis Lethal Factor)
  7. R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
  8. M. Zasloff, Nature, 415, 389 (2002). (Review)
  9. T. Hirsch, F. Jacobsen, H.-U. Steinau, and L. Steinstraesser, Protein Pept. Lett., 15, 238 (2008). (Review)
  10. M. Pazgier, X. Li, W. Lu, and J. Lubkowski, Curr. Pharm. Des., 13, 3096 (2007). (Review)

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