α-Defensin-2 (Human)

Code:
4428-s
Name:
α-Defensin-2 (Human)
HNP-2 (Human Neutrophil Peptide-2)
Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys (Disulfide bonds between Cys1-Cys29, Cys3-Cys18, and Cys8-Cys28)
(M.W. 3371.0) C147H217N43O37S6
Antimicrobial Peptide
Package Price(Yen) Availability Quantity  
Vial 0.1 mg 20,000 Ships within
1-3 business days

main

Purity:
≧99.0% (HPLC)
Other Name:
α-ディフェンシン-2
α-デフェンシン-2
Storage:
-20 ℃
Production:
Synthetic Product

more information

CAS Registry Number:
120721-97-3
Category:
Biologically Active Peptides

reference

  1. T. Ganz, M.E. Selsted, D. Szklarek, S.S.L. Harwig, K. Daher, D.F. Bainton, and R.I. Lehrer, J. Clin. Invest., 76, 1427 (1985). (Original; Isolation)
  2. M.E. Selsted, S.S.L. Harwig, T. Ganz, J.W. Schilling, and R.I. Lehrer, J. Clin. Invest., 76, 1436 (1985). (Original; Structure)
  3. F.T. Lundy, D.F. Orr, J.R. Gallagher, P. Maxwell, C. Shaw, S.S. Napier, C.G. Cowan, P.-J. Lamey, and J.J. Marley, Oral Oncol., 40, 139 (2004). (Pharmacol.; HNP in Squamous Cell Carcinoma)
  4. F.T. Lundy, D.F. Orr, C. Shaw, P.-J. Lamey, and G.J. Linden, Mol. Immunol., 42, 575 (2005). (Pharmacol.; HNP in Gingival Crevicular Fluid)
  5. C. Kim, N. Gajendran, H.-W. Mittrüker, M. Weiwad, Y-H. Song, R. Hurwitz, M. Wilmanns, G. Fischer, and S.H.E. Kaufmann, Proc. Natl. Acad. Sci., U.S.A., 102, 4830 (2005). (Pharmacol.; Neutralization of Anthrax Lethal Toxin)
  6. C.B. Buck, P.M. Day, C.D. Thompson, J. Lubkowski, W. Lu, D.R. Lowy, and J.T. Schiller, Proc. Natl. Acad. Sci. U.S.A., 103, 1516 (2006). (Pharmacol.; Inhibition of Papillomavirus Infection)
  7. R.I. Lehrer, T. Ganz, D. Szklarek, and M.E. Selsted, J. Clin. Invest., 81, 1829 (1988). (Pharmacol.;Activity difference in HNP)
  8. S. Kubo, K. Tanimura, H. Nishio, N. Chino, T. Teshima, T. Kimura, and Y. Nishiuchi, Int. J. Pept. Res. Ther., 14, 341 (2008). (Chem. Synthesis & Pharmacol.)
  9. R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
  10. M. Zasloff, Nature, 415, 389 (2002). (Review)

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