ProTx-I
- Code:
- 4409-s
- Name:
- ProTx-I
- Glu-Cys-Arg-Tyr-Trp-Leu-Gly-Gly-Cys-Ser-Ala-Gly-Gln-Thr-Cys-Cys-Lys-His-Leu-Val-Cys-Ser-Arg-Arg-His-Gly-Trp-Cys-Val-Trp-Asp-Gly-Thr-Phe-Ser (Disulfide bonds between Cys2-Cys16, Cys9-Cys21, and Cys15-Cys28)
- (M.W. 3987.5) C171H245N53O47S6
- T-Type Ca2+ Channel / Na+ Channel / K+ Channel Blocker (Gating Modifier)
- main
- more information
- reference
main
- Purity:
- ≧97.0% (HPLC)
- Storage:
- -20 ℃
- Source:
- Tarantula, Thrixopelma pruriens
- Production:
- Synthetic Product
Solubility: H2O (0.1 mM)
more information
- Category:
- Biologically Active Peptides
reference
- R.E. Middleton, V.A. Warren, R.L. Kraus, J.C. Hwang, C.J. Liu, G. Dai, R.M. Brochu, M.G. Kohler, Y.-D. Gao, V.M. Garsky, M.J. Bogusky, J.T. Mehl, C.J. Cohen, and M.M. Smith, Biochemistry, 41, 14734 (2002). (Original)
- T. Ohkubo, J. Yamazaki, and K. Kitamura, J. Pharmacol. Sci., 112, 452 (2010). (Pharmacol.)
- B.T. Priest, K.M. Blumenthal, J.J. Smith, V.A. Warren, and M.M. Smith, Toxicon, 49, 194 (2007). (Review)
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