β-Defensin-4 (Human)

Glu-Leu-Asp-Arg-Ile-Cys-Gly-Tyr-Gly-Thr-Ala-Arg-Cys-Arg-Lys-Lys-Cys-Arg-Ser-Gln-Glu-Tyr-Arg-Ile-Gly-Arg-Cys-Pro-Asn-Thr-Tyr-Ala-Cys-Cys-Leu-Arg-Lys (Disulfide bonds between Cys⁶-Cys³³, Cys¹³-Cys²⁷, and Cys¹⁷-Cys³⁴)
: (M.W. 4366.0) C₁₈₀H₂₉₅N₆₃O₅₂S₆
: Antimicrobial Peptide / Chemoattractant for Monocytes

Package	Price(Yen)	Availability	Quantity
Vial 0.1 mg	22,000	Ships within 1-3 business days
バルク見積もり

Solubility: H₂O (0.1 mM)

B.C. Schutte, J.P. Mitros, J.A. Bartlett, J.D. Walters, H. Peng Jia, M.J. Welsh, T.L. Casavant, and P.B. McCray, Jr., Proc. Natl. Acad. Sci. U.S.A., 99, 2129 (2002). (β-Defensin Family Peptides)
J.-R.C. Garcia, A. Krause, S. Schulz, F.-J. Rodriguez-Jiménez, E. Klüver, K. Adermann, U. Forssmann, A. Frimpong-Boateng, R. Bals, and W.-G. Forssmann, FASEB J., 15, 1819 (2001). (Original; hBD-4 & S-S Bond)
S. Yanagi, J.-i. Ashitani, H. Ishimoto, Y. Date, H. Mukae, N. Chino, and M. Nakazato, Respiratory Res., 6, 130 (2005). (Pharmacol. & Immunohistochem.)
X. Chen, F. Niyonsaba, H. Ushio, M. Hara, H. Yokoi, K. Matsumoto, H. Saito, I. Nagaoka, S. Ikeda, K. Okumura, and H. Ogawa, Eur. J. Immunol., 37, 434 (2007). (Pharmacol.)
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M. Zasloff, Nature, 415, 389 (2002). (Review)
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M. Pazgier, X. Li, W. Lu, and J. Lubkowski, Curr. Pharm. Des., 13, 3096 (2007). (Review)
Y. Lai and R.L. Gallo, Trends Immunol., 30, 131 (2009). (Review)