β-Defensin-4 (Human)

Code:
4406-s
Name:
β-Defensin-4 (Human)
hBD-4
Glu-Leu-Asp-Arg-Ile-Cys-Gly-Tyr-Gly-Thr-Ala-Arg-Cys-Arg-Lys-Lys-Cys-Arg-Ser-Gln-Glu-Tyr-Arg-Ile-Gly-Arg-Cys-Pro-Asn-Thr-Tyr-Ala-Cys-Cys-Leu-Arg-Lys (Disulfide bonds between Cys6-Cys33, Cys13-Cys27, and Cys17-Cys34)
(M.W. 4366.0) C180H295N63O52S6
Antimicrobial Peptide / Chemoattractant for Monocytes
Package Price(Yen) Availability Quantity  
Vial 0.1 mg 22,000 Ships within
1-3 business days

main

Purity:
≧97.0% (HPLC)
Other Name:
BD-4 (human)
β-デフェンシン-4
Storage:
-20 ℃
Production:
Synthetic Product

more information

CAS Registry Number:
370570-43-7
Category:
Biologically Active Peptides

reference

  1. B.C. Schutte, J.P. Mitros, J.A. Bartlett, J.D. Walters, H. Peng Jia, M.J. Welsh, T.L. Casavant, and P.B. McCray, Jr., Proc. Natl. Acad. Sci. U.S.A., 99, 2129 (2002). (β-Defensin Family Peptides)
  2. J.-R.C. Garcia, A. Krause, S. Schulz, F.-J. Rodriguez-Jiménez, E. Klüver, K. Adermann, U. Forssmann, A. Frimpong-Boateng, R. Bals, and W.-G. Forssmann, FASEB J., 15, 1819 (2001). (Original; hBD-4 & S-S Bond)
  3. S. Yanagi, J.-i. Ashitani, H. Ishimoto, Y. Date, H. Mukae, N. Chino, and M. Nakazato, Respiratory Res., 6, 130 (2005). (Pharmacol. & Immunohistochem.)
  4. X. Chen, F. Niyonsaba, H. Ushio, M. Hara, H. Yokoi, K. Matsumoto, H. Saito, I. Nagaoka, S. Ikeda, K. Okumura, and H. Ogawa, Eur. J. Immunol., 37, 434 (2007). (Pharmacol.)
  5. N. Chino, S. Kubo, H. Nishio, Y. Nishiuchi, M. Nakazato, and T. Kimura, Int. J. Pept. Res. Ther., 12, 203 (2006). (Chem. Synthesis & Pharmacol.)
  6. R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
  7. M. Zasloff, Nature, 415, 389 (2002). (Review)
  8. T. Hirsch, F. Jacobsen, H.-U. Steinau, and L. Steinstraesser, Protein Pept. Lett., 15, 238 (2008). (Review)
  9. M. Pazgier, X. Li, W. Lu, and J. Lubkowski, Curr. Pharm. Des., 13, 3096 (2007). (Review)
  10. Y. Lai and R.L. Gallo, Trends Immunol., 30, 131 (2009). (Review)

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