Muscarinic Toxin 1

Leu-Thr-Cys-Val-Thr-Ser-Lys-Ser-Ile-Phe-Gly-Ile-Thr-Thr-Glu-Asn-Cys-Pro-Asp-Gly-Gln-Asn-Leu-Cys-Phe-Lys-Lys-Trp-Tyr-Tyr-Ile-Val-Pro-Arg-Tyr-Ser-Asp-Ile-Thr-Trp-Gly-Cys-Ala-Ala-Thr-Cys-Pro-Lys-Pro-Thr-Asn-Val-Arg-Glu-Thr-Ile-Arg-Cys-Cys-Glu-Thr-Asp-Lys-Cys-Asn-Glu (Disulfide bonds between Cys³-Cys²⁴, Cys¹⁷-Cys⁴², Cys⁴⁶-Cys⁵⁸, and Cys⁵⁹-Cys⁶⁴)
: (M.W. 7509.5) C₃₂₆H₄₉₉N₈₇O₁₀₁S₈
: Agonist for Muscarinic Acetylcholine Receptor-1/4 (M₁ / M₄) (Non-specific Ligand)

Package	Price(Yen)	Availability	Quantity
Vial 0.1 mg	30,000	Ships within 1-3 business days
バルク見積もり

Solubility: H₂O (50 μM)

M. Jolkkonen, A. Adem, U. Hellman, C. Wernstedt, and E. Karlsson, Toxicon, 33, 399 (1995). (Original; Structure)
D. Jerusalinsky and A.L. Harvey, Trends Pharmacol. Sci., 15, 424 (1994). (Review; Toxin for Muscarinic Receptor)
A. Adem and E. Karlsson, Life Sci., 60, 1069 (1997). (Pharmacol.)
H.Nishio, Y. Nishiuchi, T. Inui, K.N. Bradley, A.L. Harvey, and T. Kimura, Peptide Science 1999, 125 (2000). (S-S Bond)
K.N. Bradley, Pharmacol. Ther., 85, 87 (2000). (Review)
L.T. Potter, Life Sci., 68, 2541 (2001). (Review)
D. Servent and C. Fruchart-Gaillard, J. Neurochem., 109, 1193 (2009). (Review)
E. Karlsson, M. Jolkkonen, E. Mulugeta, P. Onali, and A. Adem, Biochimie, 82, 793 (2000). (Review)