CA-074
- Code:
- 4322-v
- Name:
- CA-074
- [(2S,3S)-3-Propylcarbamoyloxirane-2-carbonyl]-L-isoleucyl-L-proline
- (M.W. 383.44) C18H29N3O6
- Inhibitor for Cathepsin B
- main
- more information
- reference
main
- Purity:
- ≧98.0% (HPLC)
- Other Name:
- L-trans-Epoxysuccinyl-Ile-Pro-OH propylamide
- (L-3-trans-(プロピルカルバミル)オキシラン-2-カルボニル)-L-イソロイシル-L-プロリン
- Storage:
- -20 ℃
- Production:
- Synthetic Product
Solubility: DMSO (10 mM)
more information
- Structure:
- Category:
- Enzyme Inhibitors
reference
- M. Murata, S. Miyashita, C. Yokoo, M. Tamai, K. Hanada, K. Hatayama, T. Towatari, T. Nikawa, and N. Katunuma, FEBS Lett., 280, 307 (1991). (Original; IC50)
- T. Towatari, T. Nikawa, M. Murata, C. Yokoo, M. Tamai, K. Hanada, and N. Katunuma, FEBS Lett., 280, 311 (1991). (Original; Pharmacol)
- T. Inubushi, H. Kakegawa, Y. Kishino, and N. Katsunuma, J. Biochem., 116, 282 (1994). (Biochem.)
- D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).
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