Tityustoxin Kα
- Code:
- 4313-s
- Name:
- Tityustoxin Kα
- TsTX-Kα
- Val-Phe-Ile-Asn-Ala-Lys-Cys-Arg-Gly-Ser-Pro-Glu-Cys-Leu-Pro-Lys-Cys-Lys-Glu-Ala-Ile-Gly-Lys-Ala-Ala-Gly-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro (Reported disulfide bonds between Cys7-Cys28, Cys13-Cys33, and Cys17-Cys35)
- (M.W. 3941.7) C168H275N49O46S7
- Voltage-dependent K+ Channel (A Channel) Blocker
- main
- more information
- reference
main
- Purity:
- ≧98.0% (HPLC)
- Storage:
- -20 ℃
- Source:
- Scorpion, Tityus serrulatus
- Production:
- Synthetic Product
Solubility: H2O (0.1 mM)
more information
- Category:
- Biologically Active Peptides
reference
- T.R. Werkman, T.A. Gustafson, R.S. Rogowski, M.P. Blaustein, and M.A. Rogawski, Mol. Pharmacol., 44, 430 (1993). (Original)
- R.S. Rogowski, B.K. Krueger, J.H. Collins, and M.P. Blaustein, Proc. Natl. Acad. Sci. USA, 91, 1475 (1994). (Pharmacol.)
- W.F. Hopkins, J. Pharmacol. Exp. Ther., 285, 1051 (1998). (Pharmacol.)
- K.C. Ellis, T.C. Tenenholz, H. Jerng, M. Hayhurst, C.S. Dudlak, W.F. Gilly, M.P. Blaustein, and D.J. Weber, Biochemistry, 40, 5942 (2001). (S-S Bond)
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