Calcicludine
- Code:
- 4310-s
- Name:
- Calcicludine
- CaC
- Trp-Gln-Pro-Pro-Trp-Tyr-Cys-Lys-Glu-Pro-Val-Arg-Ile-Gly-Ser-Cys-Lys-Lys-Gln-Phe-Ser-Ser-Phe-Tyr-Phe-Lys-Trp-Thr-Ala-Lys-Lys-Cys-Leu-Pro-Phe-Leu-Phe-Ser-Gly-Cys-Gly-Gly-Asn-Ala-Asn-Arg-Phe-Gln-Thr-Ile-Gly-Glu-Cys-Arg-Lys-Lys-Cys-Leu-Gly-Lys (Disulfide bonds between Cys7-Cys57, Cys16-Cys40, and Cys32-Cys53)
- (M.W. 6980.1) C321H476N86O78S6
- Neuronal L-type Ca2+ Channel Blocker
- main
- more information
- reference
main
- Purity:
- ≧97.0% (HPLC)
- Storage:
- -20 ℃
- Source:
- Green Mamba, Dendroaspis angusticeps
- Production:
- Synthetic Product
Solubility: H2O (10 μM)
more information
- Category:
- Biologically Active Peptides
reference
- H. Schweitz, C. Heurteaux, P. Bois, D. Moinier, G. Romey, and M. Lazdunski, Proc. Natl. Acad. Sci. USA, 91, 878 (1994). (Original)
- H. Nishio, Y. Nishiuchi, T. Inui, M. Nakao, T.X. Watanabe, T. Kimura, and S. Sakakibara, Peptide Chemistry 1995, 113 (1996). (Chem. Synthesis & Pharmacol.)
- O.D. Uchitel, Toxicon, 35, 1161 (1997). (Review)
- J. Santos-Torres, A. Fuente, J.M. Criado, A.S. Riolobos, M. Heredia, and J. Yajeya, J. Neurosci. Res., 85, 634 (2007). (Pharmacol.)
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