μ-Conotoxin GS
- Code:
- 4263-v
- Name:
- μ-Conotoxin GS
- Ala-Cys-Ser-Gly-Arg-Gly-Ser-Arg-Cys-Hyp-Hyp-Gln-Cys-Cys-Met-Gly-Leu-Arg-Cys-Gly-Arg-Gly-Asn-Pro-Gln-Lys-Cys-Ile-Gly-Ala-His-Gla-Asp-Val (Gla:L-γ-Carboxyglutamic acid) (Disulfide bonds between Cys2-Cys14, Cys9-Cys19, and Cys13-Cys27)
- (M.W. 3618.1) C139H226N52O48S7
- Na+ Channel Blocker
- main
- more information
- reference
main
- Purity:
- ≧94.0% (HPLC)
- Storage:
- -20 ℃
- Source:
- Marine Snail, Conus geographus
- Production:
- Synthetic Product
Solubility: H2O (0.1 mM)
more information
- Category:
- Biologically Active Peptides
reference
- Y. Yanagawa, T. Abe, M. Satake, S. Odani, J. Suzuki, and K. Ishikawa, Biochemistry, 27, 6256 (1988). (Original)
- M. Nakao, Y. Nishiuchi, M. Nakata, T.X. Watanabe, T. Kimura, and S. Sakakibara, Lett. Pept. Sci., 2, 17 (1995). (Chem. Synthesis & S-S Bond)
- B.M. Olivera,W.R. Gray, R. Zeikus, J.M. McIntosh, J. Varga, J. Rivier, V. De Santos, and L.J. Cruz, Science, 230, 1338 (1985). (Review)
- W.R. Gray, B.M. Olivera, and L.J. Cruz, Annu. Rev. Biochem., 57, 665 (1988). (Review)
- R.A. Myers, L.J. Cruz, J.E. Rivier, and B.M. Olivera, Chem. Rev., 93, 1923 (1993). (Review)
- B.M. Olivera, G.P. Miljanich, J. Ramachandran, and M.E. Adams, Annu. Rev. Biochem., 63, 823 (1994). (Review)
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