(Z-Leu-Leu-NHCH2)2CO
- Code:
- 3218-v
- Name:
- (Z-Leu-Leu-NHCH2)2CO
- (Z-LL)2 Ketone
- 1,3-Bis[(benzyloxycarbonyl-L-leucyl-L-leucyl)amino]acetone
- (M.W. 809.00) C43H64N6O9
- Inhibitor for Signal Peptide Peptidase
- main
- more information
- reference
main
- Purity:
- ≧99.0% (HPLC)
- View Analytical Data Sheet
- Storage:
- -20 ℃
- Production:
- Synthetic Product
Solubility: DMSO (10 mM)
more information
- Structure:
- Category:
- Enzyme Inhibitors
reference
- A. Weihofen, M.K. Lemberg, H.L. Ploegh, M. Bogyo, and B. Martoglio, J. Biol. Chem., 275, 30951 (2000). (Original)
- A. Weihofen, K. Binns, M.K. Lemberg, K. Ashman, and B. Martoglio, Science, 296, 2215 (2002). (Signal Peptide Peptidase Inhibitor)
- A. Weihofen, M.K. Lemberg, E. Friedmann, H. Rueeger, A. Schmitz, P. Paganetti, G. Rovelli, and B. Martoglio, J. Biol. Chem., 278, 16528 (2003). (Signal Peptide Peptidase Inhibitory Activity)
- D. Leung, G. Abbenante, and D.P. Fairlie, J. Med. Chem., 43, 305 (2000).
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