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Guangxitoxin-1E
- Code:
- 4433-s
- Name:
- Guangxitoxin-1E
- GxTX-1E
- Glu-Gly-Glu-Cys-Gly-Gly-Phe-Trp-Trp-Lys-Cys-Gly-Ser-Gly-Lys-Pro-Ala-Cys-Cys-Pro-Lys-Tyr-Val-Cys-Ser-Pro-Lys-Trp-Gly-Leu-Cys-Asn-Phe-Pro-Met-Pro (Disulfide bonds between Cys4-Cys19, Cys11-Cys24, and Cys18-Cys31)
- (Trifluoroacetate Form)
- (M.W. 3948.6) C178H248N44O45S7
- Kv2.1/Kv2.2 Channel Blocker / Enhancer of Glucose-Dependent Insulin Secretion
| Package | Price(Yen) | Availability |
|---|---|---|
| Vial 0.1 mg | 22,000 |
Ships within 1-3 business days |
| Bulk Request | ||
- main
- more information
- reference
main
- Purity:
- ≧96.0% (HPLC)
- View Analytical Data Sheet
- Storage:
- -20 ℃
- Source:
- Tarantula, Plesiophrictus guangxiensis sp. nov.
- Production:
- Synthetic Product
Solubility: H2O (0.1 mM)
more information
- Category:
- Biologically Active Peptides
reference
- J. Herrington, Y.-P. Zhou, R.M. Bugianesi, P.M. Dulski, Y. Feng, V.A. Warren, M.M. Smith, M.G. Kohler, V.M. Garsky, M. Sanchez, M. Wagner, K. Raphaelli, P. Banerjee, C. Ahaghotu, D. Wunderler, B.T. Priest, J.T. Mehl, M.L. Garcia, O.B. McManus, G.J. K, Diabetes, 55, 1034 (2006). (Original)
- P.E. MacDonald, S. Sewing, J. Wang, J.W. Joseph, P.E. MacDonald, S. Sewing, J. Wang, J.W. Joseph, S.R. Smukler, G. Sakellaropoulos, J.Wang, M.C. Saleh, C.B. Chan,R.G. Tsushima, A.M.F. Salapatek, and M.B. Wheeler, J. Biol. Chem., 277, 44938 (2002). (Pharmacol.; Role of Kv2.1 in Glucose-Dependent Insulin Secretion)
- N.A. Tamarina, A. Kuznetsov, L.E. Fridlyand, and L.H. Philipson, Am. J. Physiol. Endocrinol. Metab., 289, E578 (2005). (Pharmacol.; Role of Kv2.1 in Glucose-Dependent Ca2+ response)
- J. Herrington, Toxicon, 49, 231 (2007). (Review)
- S. Lee, M. Milescu, H.H. Jung, J.Y. Lee, C.H. Bae, C.W. Lee, H.H. Kim, K.J. Swartz, and J.I. Kim, Biochemistry, 49, 5134 (2010). (Solution Structure & S-S Bond)
SDS: Search other product
