Imperatoxin A

Code:
4343-s
Name:
Imperatoxin A
IpTxa
Gly-Asp-Cys-Leu-Pro-His-Leu-Lys-Arg-Cys-Lys-Ala-Asp-Asn-Asp-Cys-Cys-Gly-Lys-Lys-Cys-Lys-Arg-Arg-Gly-Thr-Asn-Ala-Glu-Lys-Arg-Cys-Arg (Reported disulfide bonds between Cys3-Cys17, Cys10-Cys21, and Cys16-Cys32)
(M.W. 3758.4) C148H254N58O45S6
Activator of Ca2+ Release Channels/Ryanodine Receptors
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Purity:
≧94.0% (HPLC)
Storage:
-20 ℃
Source:
Scorpion, Pandinus imperator
Production:
Synthetic Product

Solubility: H2O (0.1 mM)

more information

Category:
Biologically Active Peptides

reference

  1. H.H. Valdivia, M.S. Kirby, W.J. Lederer, and R.Coronado, Proc. Natl. Acad. Sci. USA, 89, 12185 (1992). (Pharmacol.)
  2. R. El-Hayek, A.J. Lokuta, C. Arévalo, and H.H. Valdivia, J. Biol. Chem., 270, 28696 (1995). (Pharmacol.)
  3. F.Z. Zamudio, G.B. Gurrola, C. Arévalo, R. Sreekumar, J.W. Walker, H.H. Valdivia, and L.D. Possani, FEBS Lett., 405, 385 (1997). (Original; Structure)
  4. K. Takeuchi, J.I. Kim, H. Takahashi, K. Sato, and I. Shimada, Peptide Science 1999, 307 (2000). (S-S Bond)

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