4343-s Imperatoxin A

Code:
4343-s
Name:
Imperatoxin A
IpTxa
Gly-Asp-Cys-Leu-Pro-His-Leu-Lys-Arg-Cys-Lys-Ala-Asp-Asn-Asp-Cys-Cys-Gly-Lys-Lys-Cys-Lys-Arg-Arg-Gly-Thr-Asn-Ala-Glu-Lys-Arg-Cys-Arg (Reported disulfide bonds between Cys3-Cys17, Cys10-Cys21, and Cys16-Cys32)
(M.W. 3758.4) C148H254N58O45S6
Activator of Ca2+ Release Channels/Ryanodine Receptors
Package Price(Yen)
Vial 0.1 mg 22,000

main

Purity:
≧94.0% (HPLC)
Storage:
-20 ℃
Source:
Scorpion, Pandinus imperator
Production:
Synthetic Product

Solubility: H2O (0.1 mM)

more information

CAS Registry Number:
172451-37-5
Category:
Biologically Active Peptides

reference

  1. H.H. Valdivia, M.S. Kirby, W.J. Lederer, and R.Coronado, Proc. Natl. Acad. Sci. USA, 89, 12185 (1992). (Pharmacol.)
  2. R. El-Hayek, A.J. Lokuta, C. Arévalo, and H.H. Valdivia, J. Biol. Chem., 270, 28696 (1995). (Pharmacol.)
  3. F.Z. Zamudio, G.B. Gurrola, C. Arévalo, R. Sreekumar, J.W. Walker, H.H. Valdivia, and L.D. Possani, FEBS Lett., 405, 385 (1997). (Original; Structure)
  4. K. Takeuchi, J.I. Kim, H. Takahashi, K. Sato, and I. Shimada, Peptide Science 1999, 307 (2000). (S-S Bond)