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ω-Agatoxin TK
- Code:
- 4294-s
- Name:
- ω-Agatoxin TK
-
ω-Aga-TK
ω-Aga-IVB
- Glu-Asp-Asn-Cys-Ile-Ala-Glu-Asp-Tyr-Gly-Lys-Cys-Thr-Trp-Gly-Gly-Thr-Lys-Cys-Cys-Arg-Gly-Arg-Pro-Cys-Arg-Cys-Ser-Met-Ile-Gly-Thr-Asn-Cys-Glu-Cys-Thr-Pro-Arg-Leu-Ile-Met-Glu-Gly-Leu-D-Ser-Phe-Ala (Reported disulfide bonds between Cys4-Cys20, Cys12-Cys25, Cys19-Cys36, and Cys27-Cys34)
- (M.W. 5273.0) C215H337N65O70S10
- P-type Ca2+ Channel Blocker
| Package | Price(Yen) | Availability |
|---|---|---|
| Vial 0.1 mg | 30,000 |
Ships within 1-3 business days |
| Bulk Request | ||
- main
- more information
- reference
main
- Purity:
- ≧95.0% (HPLC)
- Storage:
- -20 ℃
- Source:
- Funnel Web Spider, Agelenopsis aperta
- Production:
- Synthetic Product
Solubility: H2O (0.1 mM)
more information
- Category:
- Biologically Active Peptides
reference
- M. Kuwada, T. Teramoto, K.Y. Kumagaye, K. Nakajima, T. Watanabe, T. Kawai, Y. Kawakami, T. Niidome, K. Sawada, Y. Nishizawa, and K. Katayama, Mol. Pharmacol., 46, 587 (1994). (Original)
- Y. Shikata, T. Watanabe, T. Teramoto, A. Inoue, Y. Kawakami, Y. Nishizawa, K. Katayama, and M. Kuwada, J. Biol. Chem., 270, 16719 (1995). (L-Ser to D-Ser Isomerase)
- M.E. Adams, I.M. Mintz, M.D. Reily, V. Thanabal, and B.P. Bean, Mol. Pharmacol., 38, 681 (1990). (Original; ω-Aga-IVB)
- S.D. Heck, P.R. Kelbaugh, M.E. Kelly, P.F. Thadeio, N.A. Saccomano, J.G Stroh. and R.A. Volkmann, J. Am. Chem. Soc., 116, 10426 (1994). (S-S Bond; ω-Aga-IVB)
- T. Teramoto, T. Niidome, M. Kimura, M. Ohgoh, Y. Nishizawa, K. Katayama, T. Mayumi, and K. Sawada, Brain Res., 756, 225 (1997). (Pharmacol.)
- S.P. Lieske and J.-M. Ramirez, J. Neurophysiol., 95, 1323 (2006). (Pharmacol.)
- B.M. Olivera, G.P. Miljanich, J. Ramachandran, and M.E. Adams, Annu. Rev. Biochem., 63, 823 (1994). (Review)
- O.D. Uchitel, Toxicon, 35, 1161 (1997). (Review)
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