Relaxin-2 (Human)

Code:
4509-v
Name:
Relaxin-2 (Human)
H2 Relaxin/Serelaxin
A-chain: Pyr-Leu-Tyr-Ser-Ala-Leu-Ala-Asn-Lys-Cys-Cys-His-Val-Gly-Cys-Thr-Lys-Arg-Ser-Leu-Ala-Arg-Phe-Cys
B-chain: Asp-Ser-Trp-Met-Glu-Glu-Val-Ile-Lys-Leu-Cys-Gly-Arg-Glu-Leu-Val-Arg-Ala-Gln-Ile-Ala-Ile-Cys-Gly-Met-Ser-Thr-Trp-Ser
(Disulfide bonds between CysA10-CysA15, CysA11-CysB11, and CysA24-CysB23)
(Trifluoroacetate Form)
(M.W. 5963.0) C256H408N74O74S8
Hormone of Pregnancy, also known as an Auto/Paracrine in Many Tissues in Both Male and Female
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Purity:
≧97.0% (HPLC)
Storage:
-20 ℃

Solubility: H2O (0.1 mM)

more information

Category:
Biologically Active Peptides

reference

  1. P. Hudson, M. John, R. Crawford, J. Haralambidis, D. Scanlon, J. Gorman, G. Tregear, J. Shine, and H. Niall, EMBO J., 3, 2333 (1984). (Original; cDNA Seq)
  2. J.T. Stults, J.H. Bourell, E. Canova-Davis, V.T. Ling, G.R. Laramee, J.W. Winslow, P.R. Griffin, E. Rinderknecht, and R.L. Vandlen, Biomed. Environ. Mass Spectrom., 19, 655 (1990). (Chem. Structure)
  3. E.E. Buellesbach, and C. Schwabe, J. Biol. Chem., 266, 10754 (1991). (Chem. Synthesis & Bioactivity)
  4. X.J. Du, R.A. Bathgate, C.S. Samuel, A.M. Dart, and R.J. Summers, Nat. Rev. Cardiol., 7, 48 (2010). (Review)
  5. S. Von Haehling, Expert Opin. Investig. Drugs, 22, 933 (2013). (Review; Meeting Highlight)
  6. N.A. Patil, K.J. Rosengren, F. Separovic, J.D. Wade, R.A.D. Bathgate, and M.A. Hossain, Br. J. Pharmacol., 174, 950 (2017). (Review)

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