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α-Defensin-6 (Human)
- Code:
- 4458-s
- Name:
- α-Defensin-6 (Human)
- [HD-6 (Human Defensin-6)]
- Ala-Phe-Thr-Cys-His-Cys-Arg-Arg-Ser-Cys-Tyr-Ser-Thr-Glu-Tyr-Ser-Tyr-Gly-Thr-Cys-Thr-Val-Met-Gly-Ile-Asn-His-Arg-Phe-Cys-Cys-Leu (Disulfide bonds between Cys4-Cys31, Cys6-Cys20, and Cys10-Cys30)
- (M.W. 3708.2) C156H228N46O46S7
- Antimicrobial Peptide in Paneth Cells
| Package | Price(Yen) | Availability |
|---|---|---|
| Vial 0.1 mg | 22,000 |
Ships within 1-3 business days |
| Bulk Request | ||
- main
- more information
- reference
main
- Purity:
- ≧98.0% (HPLC)
- View Analytical Data Sheet
- Other Name:
- α-ディフェンシン-6
- α-デフェンシン-6
- Storage:
- -20 ℃
- Production:
- Synthetic Product
Solubility: H2O (0.1 mM)
more information
- Category:
- Biologically Active Peptides
reference
- D.E. Jones and C.L. Bevins, FEBS Lett., 315, 187 (1993). (Original;mRNA Seq.)
- E.M. Porter, M.A. Poles, J.S. Lee, J. Naitoh, C.L. Bevins, and T. Ganz, FEBS Lett., 434, 272 (1998). (Endogenous Form)
- B. Ericksen, Z. Wu, W. Lu, and R.I. Lehrer, Antimicrob. Agents Chemother., 49, 269 (2005). (Pharmacol.; No Antibacterial Activity)
- J. Wehkamp, K. Schmidt, K.R. Herrlinger, S. Baxmann, S. Behling, C. Wohlschläger, A.C. Feller, E.F. Stange, and K. Fellermann, J. Clin. Pathol., 56, 352 (2003). (Pharmacol.; Enhanced Expression in Helicobacter pylori Infection)
- E. Hazrati, B. Galen, W. Lu, W. Wang, Y. Ouyang, M.J. Keller, R.I. Lehrer. and B.C. Herold, J. Immunol., 177, 8658 (2006). (Pharmacol.; Inhibition of Herpes Simplex Virus Infection)
- M. Doss, M.R. White, T. Tecle, D. Gantz, E.C. Crouch, G. Jung, P. Ruchala, A.J. Waring, R.I. Lehrer, and K.L. Hartshorn, J. Immunol., 182, 7878 (2009). (Pharmacol.; Influenza A Virus Neutralizing Activity)
- M.J. Koslowski, J. Beisner, E.F. Stange, and J. Wehkamp, Int. J. Med. Microbiol., 300, 34 (2010). (Minireview; Antimicrobial Host Defense in Small Crohn's Disease)
- M.E. Klotman, A. Rapista, N. Teleshova, A. Micsenyi, G.A. Jarvis, W. Lu, E. Porter, and T.L. Chang, J. Immunol., 180, 6176 (2008). (Pharmacol.; Enhancement of HIV Infectivity)
- R.I. Lehrer and T. Ganz, Ann. N. Y. Acad. Sci., 797, 228 (1996). (Review)
- M. Zasloff, Nature, 415, 389 (2002). (Review)
- T. Hirsch, F. Jacobsen, H.-U. Steinau, and L. Steinstraesser, Protein Pept. Lett., 15, 238 (2008). (Review)
- M. Pazgier, X. Li, W. Lu, and J. Lubkowski, Curr. Pharm. Des., 13, 3096 (2007). (Review)
- Y. Lai and R.L. Gallo, Trends Immunol., 30, 131 (2009). (Review)
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