Plectasin

Code:
4432-s
Name:
Plectasin
Gly-Phe-Gly-Cys-Asn-Gly-Pro-Trp-Asp-Glu-Asp-Asp-Met-Gln-Cys-His-Asn-His-Cys-Lys-Ser-Ile-Lys-Gly-Tyr-Lys-Gly-Gly-Tyr-Cys-Ala-Lys-Gly-Gly-Phe-Val-Cys-Lys-Cys-Tyr (Disulfide bonds between Cys4-Cys30, Cys15-Cys37, and Cys19-Cys39)
(M.W. 4401.9) C189H267N53O56S7
Antimicrobial Peptide
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Purity:
≧98.0% (HPLC)
Storage:
-20 ℃
Source:
Fungus, Pseudoplectania nigrella
Production:
Synthetic Product

Solubility: H2O (0.1 mM)

more information

Category:
Biologically Active Peptides

reference

  1. P.H. Mygind, R.L. Fischer, K.M. Schnorr, M.T. Hansen, C.P. Sönksen, S. Ludvigsen, D. Raventós, S. Buskov, B. Christensen, L. De Maria, O. Taboureau, D. Yaver, S.G. Elvig-Jørgensen, M.V. Sørensen, B.E. Christensen, S. Kjaerul, Nature, 437, 975 (2005). (Original; Structure & Antimicrobial Activity)
  2. S. Hara, H. Mukae, N. Sakamoto, H. Ishimoto, M. Amenomori, H. Fujita, Y. Ishimatsu, K. Yanagihara, S. Kohno, Biochem. Biophys. Res. Commun., 374, 709 (2008). (Pharmacol.)
  3. K. Mandal, B.L. Pentelute, V. Tereshko, V. Thammavongsa, O. Schneewind, A.A. Kossiakoff, and S.B.H. Kent, Protein Sci., 18, 1146 (2009). (X-ray Structure)
  4. T. Schneider, T. Kruse, R. Wimmer, I. Wiedemann, V. Sass, U. Pag, A. Jansen, A.K. Nielsen, P.H. Mygind, D.S. Raventos, S. Neve, B. Ravn, A.M. Bonvin, L. De Maria, A.S. Andersen, L.K. Gammelgaard, H.G. Sahl, and H.H. Kristensen, Science, 328, 1168 (2010). (Pharmacol.)

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