D-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin

Code:
4293-v
Name:
D-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin
Hoe 140, Icatibant
D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg (Thi: L-Thienylalanine, Tic: 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid,Oic: (3aS,7aS)-Octahydroindolyl-2-carboxylic acid)
(M.W. 1304.5) C59H89N19O13S
Bradykinin B2-Receptor Antagonist
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Purity:
≧99.0% (HPLC)
Storage:
-20 ℃
Production:
Synthetic Product

Solubility: H2O (0.1 mM)

more information

Category:
Biologically Active Peptides

reference

  1. F.J. Hock, K. Wirth, U. Albus, W. Linz, H.J. Gerhards, G. Wiemer, St. Henke, G. Breipohl, W. König, J. Knolle, and B.A. Schölkens, Br. J. Pharmacol., 102, 769 (1991). (Original & Pharmacol.; in vitro)
  2. K. Wirth, F.J. Hock, U. Albus, W. Linz, H.G. Alpermann, H. Anagnostopoulos, S. Henke, G. Breipohl, W. König, J. Knolle, and B.A. Schölkens, Br. J. Pharmacol., 102, 774 (1991). (Original & Pharmacol.; in vivo)
  3. A.R. Baydon and B. Woodward, Br. J. Pharmacol., 103, 1829 (1991). (Pharmacol.)
  4. G. Wiemer, R. Popp, B.A. Schölkens, and H. Gögelein, Brain Res., 638, 261 (1994). (Pharmacol.; Icatibant)
  5. Handbook of Experimental Pharmacology, Bradykinin, Kallidin and Kallikrein, (E.G. Erdös, ed.), Springer-Verlag, Berlin, Vol. 25, (1970). (Review)
  6. Handbook of Experimental Pharmacology, Bradykinin, Kallidin and Kallikrein, (E.G. Erdös, ed.), Springer-Verlag, Berlin, Vol. 25, Suppl., (1979). (Review)

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